Exosomes for CRISPR-Cas9 Delivery: The Cutting Edge in Genome Editing

C Aslan, NM Zolbanin, F Faraji, R Jafari - Molecular Biotechnology, 2023 - Springer
Gene mutation correction was challenging until the discovery of clustered regularly
interspaced short palindromic repeats (CRISPR) and CRISPR-associated protein (Cas) …

Multiplex CRISPR/Cas9 genome editing in hematopoietic stem cells for fetal hemoglobin reinduction generates chromosomal translocations

C Samuelson, S Radtke, H Zhu, M Llewellyn… - … Therapy-Methods & …, 2021 - cell.com
Sickle cell disease and β-thalassemia are common monogenic disorders that cause
significant morbidity and mortality globally. The only curative treatment currently is …

CRISPR Gene Therapy: A Promising One-Time Therapeutic Approach for Transfusion-Dependent β-Thalassemia—CRISPR-Cas9 Gene Editing for β-Thalassemia

U Gamage, K Warnakulasuriya, S Hansika… - Thalassemia …, 2023 - mdpi.com
β-Thalassemia is an inherited hematological disorder that results from genetic changes in
the β-globin gene, leading to the reduced or absent synthesis of β-globin. For several …

Detection of genes responsible for cetuximab sensitization in colorectal cancer cells using CRISPR-Cas9

T Hu, J Yang, Y Yan, Y Chen, H Xue… - Bioscience …, 2020 - portlandpress.com
Colorectal cancer (CRC) is a common malignant tumor in digestive tract with highly invasive
and metastatic capacity. Drug sensitivity remains a significant obstacle to successful …

The Utilization of CRISPR/Cas9 in Monogenic Disorders Authors

SM Mellor - Spectra Undergraduate Research Journal, 2022 - digitalscholarship.unlv.edu
This paper is a literature review of various scientific research papers, exploring the recent
scientific advancement in the field of genetic engineering. The research presented is a …

Revolutionizing Sickle Cell Disease Treatment: Unveiling CRISPR and Lentiviral Therapies—Navigating Complexities in Access, Equity, and Global Health Dynamics

P Ashinze - Plasmatology, 2024 - journals.sagepub.com
Advancing Sickle Cell Disease Treatment: Addressing Access Challenges In this editorial,
we discuss the recent approval by the US Food and Drug Administration (FDA) of two new …

[PDF][PDF] Therapeutic trends and perspectives in Diamond Blackfan anemia

MT Vulpe - Hemostasis Thrombosis and Anemic Syndromes, 2023 - htas.umfcd.ro
Coperta rev hema 2023_revista Page 1 HEMOSTASIS, THROMBOSIS AND ANEMIC
SYNDROMES VOLUME I, NO. 2, 2023 30 Literature Review Therapeutic Trends and …

CRISPR gene editing: a revolution in progress

M Greener - Prescriber, 2022 - Wiley Online Library
CRISPR gene editing: a revolution in progress - Greener - 2022 - Prescriber - Wiley Online
Library Skip to Article Content Skip to Article Information Wiley Clinical Healthcare Hub Wiley …

Advancement of CRISPR-Cas9 Technology in Clinical Research

B Srivastava, PB Reddy - Productivity, 2021 - search.proquest.com
CRISPR has emerged recently as a powerful molecular tool to quickly alter any mutated
sequence ofDNAin any gene accurately. Scientists have found it to be more efficient and …