Ischaemia reperfusion injury in liver transplantation: Cellular and molecular mechanisms
WA Dar, E Sullivan, JS Bynon, H Eltzschig… - Liver …, 2019 - Wiley Online Library
Liver disease causing end organ failure is a growing cause of mortality. In most cases, the
only therapy is liver transplantation. However, liver transplantation is a complex undertaking …
only therapy is liver transplantation. However, liver transplantation is a complex undertaking …
[HTML][HTML] Role of immuno-inflammatory signals in liver ischemia-reperfusion injury
Ischemia reperfusion injury (IRI) is a major obstacle in liver resection and liver
transplantation. The initial step of IRI is mediated through ischemia which promotes the …
transplantation. The initial step of IRI is mediated through ischemia which promotes the …
Dual-responsive biohybrid neutrobots for active target delivery
Swimming biohybrid microsized robots (eg, bacteria-or sperm-driven microrobots) with self-
propelling and navigating capabilities have become an exciting field of research, thanks to …
propelling and navigating capabilities have become an exciting field of research, thanks to …
[HTML][HTML] The role of cytokines in neutrophil development, tissue homing, function and plasticity in health and disease
M Tsioumpekou, D Krijgsman, JHW Leusen… - Cells, 2023 - mdpi.com
Neutrophils are crucial innate immune cells and comprise 50–70% of the white blood cell
population under homeostatic conditions. Upon infection and in cancer, blood neutrophil …
population under homeostatic conditions. Upon infection and in cancer, blood neutrophil …
Regulation and functional roles of chemokines in liver diseases
S Cao, M Liu, TS Sehrawat, VH Shah - Nature reviews Gastroenterology …, 2021 - nature.com
Inflammation is a major contributor to the pathogenesis of almost all liver diseases. Low-
molecular-weight proteins called chemokines are the main drivers of liver infiltration by …
molecular-weight proteins called chemokines are the main drivers of liver infiltration by …
The evolving role of liver sinusoidal endothelial cells in liver health and disease
MJ McConnell, E Kostallari, SH Ibrahim, Y Iwakiri - Hepatology, 2023 - journals.lww.com
LSECs are a unique population of endothelial cells within the liver and are recognized as
key regulators of liver homeostasis. LSECs also play a key role in liver disease, as …
key regulators of liver homeostasis. LSECs also play a key role in liver disease, as …
[HTML][HTML] The roles of neutrophils in the pathogenesis of liver diseases
J Tang, Z Yan, Q Feng, L Yu, H Wang - Frontiers in Immunology, 2021 - frontiersin.org
Neutrophils are the largest population of circulating leukocytes and the first responder
against invading pathogens or other danger signals. Sophisticated machineries help them …
against invading pathogens or other danger signals. Sophisticated machineries help them …
[HTML][HTML] Ferroptosis—a new dawn in the treatment of organ ischemia–reperfusion injury
L Zhou, S Han, J Guo, T Qiu, J Zhou, L Shen - Cells, 2022 - mdpi.com
Ischemia–reperfusion (I/R) is a common pathological phenomenon that occurs in numerous
organs and diseases. It generally results from secondary damage caused by the recovery of …
organs and diseases. It generally results from secondary damage caused by the recovery of …
[HTML][HTML] Immune-mediated drug-induced liver injury: immunogenetics and experimental models
A Gerussi, A Natalini, F Antonangeli… - International Journal of …, 2021 - mdpi.com
Drug-induced liver injury (DILI) is a challenging clinical event in medicine, particularly
because of its ability to present with a variety of phenotypes including that of autoimmune …
because of its ability to present with a variety of phenotypes including that of autoimmune …
[HTML][HTML] Targeting oxidative stress with polyphenols to fight liver diseases
Reactive oxygen species (ROS) are important second messengers in many metabolic
processes and signaling pathways. Disruption of the balance between ROS generation and …
processes and signaling pathways. Disruption of the balance between ROS generation and …