Tuberculosis associated with HIV infection
JA Tornheim, KE Dooley - Microbiology spectrum, 2017 - Am Soc Microbiol
Tuberculosis (TB) has recently surpassed HIV as the primary infectious disease killer
worldwide, but the two diseases continue to display lethal synergy. The burden of TB is …
worldwide, but the two diseases continue to display lethal synergy. The burden of TB is …
Effectiveness and safety of antiretrovirals with rifampicin: crucial issues for high-burden countries
Coadministration of antitubercular and antiretroviral therapy is common in high-burden
countries where tuberculosis is the commonest opportunistic infection. Concomitant use of …
countries where tuberculosis is the commonest opportunistic infection. Concomitant use of …
Pharmacokinetics of efavirenz and treatment of HIV-1 among pregnant women with and without tuberculosis coinfection
Background Pregnancy and tuberculosis treatment or prophylaxis can affect efavirenz
pharmacokinetics, maternal human immunodeficiency virus type 1 (HIV-1) treatment …
pharmacokinetics, maternal human immunodeficiency virus type 1 (HIV-1) treatment …
[HTML][HTML] Long-term efavirenz pharmacokinetics is comparable between Tanzanian HIV and HIV/Tuberculosis patients with the same CYP2B6*6 genotype
The impact of anti-tuberculosis co-treatment on efavirenz (EFV) exposure is still uncertain as
contradictory reports exist, and the relevance of CYP2B6* 6 genetic polymorphism on …
contradictory reports exist, and the relevance of CYP2B6* 6 genetic polymorphism on …
High efavirenz serum concentrations in TB/HIV-coinfected Ugandan adults with a CYP2B6 516 TT genotype on anti-TB treatment
A von Braun, B Castelnuovo… - Journal of …, 2019 - academic.oup.com
Objectives To report the efavirenz serum concentrations in TB/HIV-coinfected Ugandan
adults on concomitant anti-TB treatment and analyse factors associated with elevated …
adults on concomitant anti-TB treatment and analyse factors associated with elevated …
[HTML][HTML] Prevalence of Cytochrome P450 2B6 Single Nucleotide Polymorphism in an HIV-Positive Cohort in Jos, Nigeria: Implication for HIV Therapy
Background: Africans exhibit great diversity in cytochrome P450 2B6 isoenzyme (CYP2B6),
the major enzyme in efavirenz metabolism. Aim: We examined the frequency of two …
the major enzyme in efavirenz metabolism. Aim: We examined the frequency of two …