Salicylanilides are pharmacologically active compounds with a wide spectrum of biological
effects. Halogenated salicylanilides, which have been used for decades in human and …

Niclosamide is an anthelmintic drug approved by the Food and Drug Administration (FDA).
The molecule has brought attention as a potential antiviral, antibacterial, and …

In this work, we have developed and tested a dry powder form of niclosamide made by thin-
film freezing (TFF) and administered it by inhalation to rats and hamsters to gather data …

To reduce the dosage size of amorphous solid dispersion (ASD)-based formulations, it is of
interest to devise formulation strategies that allow increased drug loading (DL) without …

This research demonstrates the influence of laser speed and the drug particle size on the
manufacturing of amorphous solid dispersions (ASD) and dosage forms thereof using …

Hesperidin is a bioflavonoid constituent that among many other biological activities shows
significant wound healing properties. However, the bioavailability of hesperidin when …

The cellulose-based polymers are extensively employed in oral formulations for addressing
ADMET issues of API. Herein, we report the synergistic effect of hydroxyethyl cellulose in …

Recent work has highlighted that amorphous solid dispersions (ASDs) containing
delamanid (DLM) and an enteric polymer, hypromellose phthalate (HPMCP), appear to be …

COVID-19 is a rapidly evolving emergency, for which there have been no specific
medication found yet. Therefore, it is necessary to find a solution for this ongoing pandemic …

Candida albicans biofilms are a complex multilayer community of cells that are resistant to
almost all classes of antifungal drugs. The bottommost layers of biofilms experience nutrient …