Gliomas are the most common primary brain tumors in adults. They arise in the glial tissue
and primarily occur in the brain. Low‐grade tumors of World Health Organization (WHO) …

Gliomas are the most common intracranial tumors. In the US, approximately 15,000 patients
die with glioblastoma per year (CBTRUS 2002). Despite modern diagnostics and treatments …

Despite advances in surgical and medical therapy, glioblastoma consistently remains a fatal
disease. Over the last 20 years, no significant increase in survival has been achieved for …

Direct communication between cells, mediated by gap junctions, is nowadays considered as
an indispensable mechanism in the maintenance of cellular homeostasis. In fact, gap …

Reduced gap junction activity has long been implicated in tumorigenesis. To elucidate the
potential role of intercellular communication in melanoma development, we examined gap …

This review focuses on the use of synthetic (non-viral) delivery systems for cancer gene
therapy. Therapeutic strategies such as gene replacement/mutation correction, immune …

While a genome‐centric paradigm in human cancer development was useful for the
understanding of some malignancies such as leukemias, causative molecular defects …

Gap‐junction channels connect the interiors of adjacent cells and can be arranged into
aggregates or plaques consisting of hundreds to thousands of channel particles. The …

Gap junctions are an important means for intercellular communication during development,
processes of tissue differentiation, and in maintenance of adult tissue homeostasis. We …

Gap junctions are intercellular channels that connect the interiors of coupled cells. We
sought to determine the extent to which malignant glioma cells form gap junction channels …