Nutritional rickets remains a global public health problem, despite effective and inexpensive
means to prevent and treat the disease. It is most prevalent in the infant/toddler age groups …

Abstract Justification Vitamin D deficiency (VDD) is being increasingly reported from India
from all age-groups. Reports suggest that VDD affects all age groups, from neonates to …

Mineral deficiencies affect millions of people worldwide and, in particular, in developing
countries. Food fortification is a valid technique used for enhancing the mineral content in …

Background: Current guidelines use differing definitions of vitamin D deficiency based on
serum 25-hydroxyvitamin D (25OHD) levels, which complicates clinical decision making on …

Low dietary calcium intakes and poor vitamin D status are common findings in children living
in developing countries. Despite many of the countries lying within the tropics and …

Defective mineralization of the growth plate and preformed osteoid result in rickets and
osteomalacia, respectively. The leading cause of rickets worldwide is solar vitamin D …

Immigrant and refugee populations bring public health challenges to host nations. In the
current global refugee crisis, children are the most vulnerable subpopulation. Diseases that …

Purpose The objective of this systematic review was to determine a minimum serum 25-
hydroxyvitamin D (25OHD) threshold based on the risk of having rickets in young children …

CYP2R1 is the principal hepatic 25-hydroxylase responsible for the hydroxylation of parent
vitamin D to 25-hydroxyvitamin D [25 (OH) D]. Serum concentrations of 25 (OH) D reflect …

Vitamin D is essential for the normal mineralization of bones during childhood. Although diet
and adequate sun exposure should provide enough of this nutrient, there is a high …