Placental multi-omics integration identifies candidate functional genes for birthweight

F Tekola-Ayele, X Zeng, S Chatterjee, M Ouidir… - Nature …, 2022 - nature.com
Abnormal birthweight is associated with increased risk for cardiometabolic diseases in later
life. Although the placenta is critical to fetal development and later life health, it has not been …

[HTML][HTML] Placental contribution to the endocrinology of gestation and parturition

G Schuler, R Fürbass, K Klisch - Animal Reproduction, 2018 - ncbi.nlm.nih.gov
In addition to many other functions, the placenta is a source of a vast number of autocrine,
paracrine and endocrine factors. However, the spectrum of placental regulatory factors, their …

AT1R-AT2R-RXFP1 functional crosstalk in myofibroblasts: impact on the therapeutic targeting of renal and cardiac fibrosis

BSM Chow, M Kocan, M Shen, Y Wang… - Journal of the …, 2019 - journals.lww.com
Background Recombinant human relaxin-2 (serelaxin), which has organ-protective actions
mediated via its cognate G protein–coupled receptor relaxin family peptide receptor 1 …

Impact of multiple factors on the incidence of developmental dysplasia of the hip: risk assessment tool

Ł Pulik, K Płoszka, K Romaniuk, A Sibilska, A Jedynak… - Medicina, 2022 - mdpi.com
Background and Objectives: Developmental dysplasia of the hip (DDH) is one of the most
common musculoskeletal conditions in children. If not treated, it leads to disability, gait …

Site-related effects of relaxin in the gastrointestinal tract through nitric oxide signalling: An updated report

R Garella, R Squecco… - Current Protein and …, 2017 - ingentaconnect.com
The peptide hormone relaxin (RLX), in addition to its effects on reproduction, has been
reported to influence gastrointestinal motility. Interestingly, the digestive tract has been …

[HTML][HTML] Relaxin influences ileal muscular activity through a dual signaling pathway in mice

E Idrizaj, R Garella, F Francini, R Squecco… - World Journal of …, 2018 - ncbi.nlm.nih.gov
AIM To investigate the signaling pathways involved in the relaxin (RLX) effects on ileal
preparations from mice through mechanical and electrophysiological experiments …

Incidence of risk factors in developmental dysplasia of the hip: a retrospective study on 18,954 cases

G Caruso, E Gambuti, E Spadoni, S Filipponi… - HIP …, 2024 - journals.sagepub.com
Background: DDH is 1 of the most important causes of childhood disability. A diagnosis of
instability can be made in the neonatal period via the Ortolani and Barlow manoeuvres …

Quantification of Relaxin-2 connecting peptide (pro-RLX2) in human blood samples

M Rehfeldt, A Sparwasser, E Funk… - The Journal of …, 2017 - academic.oup.com
Background The peptide hormone relaxin-2 is implicated in diverse physiological and
pathophysiological processes. Several assays are available for quantification of human …

“Relaxin-dependent” way of implementing spontaneous preterm labor in multiple pregnancies: The involvement of placental relaxin 2

OV Pachuliya, ON Bespalova… - … of obstetrics and …, 2021 - journals.eco-vector.com
BACKGROUND: Despite numerous studies, the etiopathogenesis of preterm birth in multiple
pregnancy remains unclear, which determines the low effectiveness of measures for the …

[HTML][HTML] «Релаксин-зависимый» путь реализации спонтанных преждевременных родов при многоплодии: вклад плацентарного релаксина-2

ОВ Пачулия, ОН Беспалова, МГ Бутенко… - … и женских болезней, 2021 - cyberleninka.ru
Актуальность. Несмотря на многочисленные исследования, этиопатогенез
преждевременных родов при многоплодии остается недостаточно ясным, что …