[HTML][HTML] Treating inflammatory bowel disease by adsorptive leucocytapheresis: a desire to treat without drugs

AR Saniabadi, T Tanaka, T Ohmori… - World Journal of …, 2014 - ncbi.nlm.nih.gov
Ulcerative colitis and Crohn's disease are the major phenotypes of the idiopathic
inflammatory bowel disease (IBD), which afflicts millions of individuals throughout the world …

Therapeutic depletion of myeloid lineage leukocytes in patients with generalized pustular psoriasis indicates a major role for neutrophils in the immunopathogenesis …

S Ikeda, H Takahashi, Y Suga, H Eto, T Etoh… - Journal of the American …, 2013 - Elsevier
BACKGROUND: Generalized pustular psoriasis (GPP) is a chronic autoimmune disease
characterized by fever, erythema, and neutrophilic pustules over large areas of the skin …

Transgenic expression of human neutrophil peptide‐1 enhances hepatic fibrosis in mice fed a choline‐deficient, L‐amino acid–defined diet

R Ibusuki, H Uto, S Arima, S Mawatari… - Liver …, 2013 - Wiley Online Library
Background Neutrophils infiltrate the livers of patients with nonalcoholic steatohepatitis
(NASH). Human neutrophil peptides (HNP s) induce cytokine and chemokine production …

Efficacy and safety of granulocyte and monocyte adsorption apheresis for ulcerative colitis: a meta-analysis

T Yoshino, H Nakase, N Minami, S Yamada… - Digestive and Liver …, 2014 - Elsevier
Background Safe and effective treatments are required for patients with ulcerative colitis. It
was suggested that granulocyte and monocyte adsorption apheresis might play an important …

Therapeutic landscape for ulcerative colitis: where is the Adacolumn® system and where should it be?

M Vecchi, P Vernia, G Riegler, R D'Incà… - Clinical and …, 2013 - Taylor & Francis
Granulocyte-monocyte apheresis is a relatively new therapy that has been proposed,
sometimes with controversial results, for the treatment of inflammatory bowel disease …

A neutralizing anti–G-CSFR antibody blocks G-CSF–induced neutrophilia without inducing neutropenia in nonhuman primates

K Scalzo-Inguanti, K Monaghan… - Journal of leukocyte …, 2017 - academic.oup.com
Neutrophils are the most abundant WBCs and have an essential role in the clearance of
pathogens. Tight regulation of neutrophil numbers and their recruitment to sites of …

[HTML][HTML] Adsorptive granulocyte and monocyte apheresis in the treatment of ulcerative colitis: the first multicenter study in China

YM Lai, WY Yao, Y He, X Jiang, YB Gu, MH Chen… - Gut and …, 2017 - ncbi.nlm.nih.gov
Methods This was a multicenter study in China involving four institutions and 34 patients
with active UC. Baseline conventional medications were continued without changing the …

Granulocyte and monocyte adsorptive apheresis ameliorates sepsis in rats

S Ma, Q Xu, B Deng, Y Zheng, H Tian, L Wang… - Intensive Care Medicine …, 2017 - Springer
Background Overwhelming activation of granulocytes and monocytes is central to
inflammatory responses during sepsis. Granulocyte and monocyte adsorptive apheresis …

The efficacy of intensive granulocyte and monocyte adsorption apheresis in a patient with Crohn's disease complicated by extensive subcutaneous aseptic …

S Kato, E Hosomi, F Amano, T Kobayashi… - Journal of Crohn's …, 2012 - academic.oup.com
Background and aims: Subcutaneous aseptic abscess is one phenotype of neutrophilic
dermatitis. We were interested to see if a case of steroid refractory Crohn's disease (CD) …

[HTML][HTML] Intensive Frequent Granulocyte Adsorptive Apheresis Therapy for Acute Fulminant Ulcerative Colitis: Two Consecutive Case Reports

Y Furuto, R Sawada, A Namikawa, N Matsuhashi… - Cureus, 2023 - ncbi.nlm.nih.gov
Granulocyte/monocyte adsorptive apheresis (GMA) therapy is a treatment method for
ulcerative colitis (UC). Twice-weekly GMA regimens are usually administered to treat severe …