The role of glutamate in neuronal ischemic injury: the role of spark in fire
BB Kostandy - Neurological Sciences, 2012 - Springer
Although being a physiologically important excitatory neurotransmitter, glutamate plays a
pivotal role in various neurological disorders including ischemic neurological diseases. Its …
pivotal role in various neurological disorders including ischemic neurological diseases. Its …
Bioenergetics of cerebral ischemia: a cellular perspective
L Hertz - Neuropharmacology, 2008 - Elsevier
In cerebral ischemia survival of neurons, astrocytes, oligodendrocytes and endothelial cells
is threatened during energy deprivation and/or following re-supply of oxygen and glucose …
is threatened during energy deprivation and/or following re-supply of oxygen and glucose …
Neurotransmitters in the mediation of cerebral ischemic injury
D Mayor, M Tymianski - Neuropharmacology, 2018 - Elsevier
Under physiological conditions, neurotransmitters shape neuronal networks and control
several cellular and synaptic functions. In the mammalian central nervous system (CNS) …
several cellular and synaptic functions. In the mammalian central nervous system (CNS) …
[PDF][PDF] NMDA receptor activation induces mitochondrial dysfunction, oxidative stress and apoptosis in cultured neonatal rat cardiomyocytes
X Gao, X Xu, J Pang, C Zhang, JM Ding… - Physiological …, 2007 - biomed.cas.cz
Glutamate is a well-characterized excitatory neurotransmitter in the central nervous system
(CNS). Recently, glutamate receptors (GluRs) were also found in peripheral tissues …
(CNS). Recently, glutamate receptors (GluRs) were also found in peripheral tissues …
Mitochondria and NMDA receptor-dependent toxicity of berberine sensitizes neurons to glutamate and rotenone injury
K Kysenius, CA Brunello, HJ Huttunen - PloS one, 2014 - journals.plos.org
The global incidence of metabolic and age-related diseases, including type 2 diabetes and
Alzheimer's disease, is on the rise. In addition to traditional pharmacotherapy, drug …
Alzheimer's disease, is on the rise. In addition to traditional pharmacotherapy, drug …
Alcohol consumption during adolescence: A link between mitochondrial damage and ethanol brain intoxication
C Tapia‐Rojas, RG Mira, AK Torres, C Jara… - Birth defects …, 2017 - Wiley Online Library
Adolescence is a period of multiple changes where social behaviors influence interpersonal‐
relations. Adolescents live new experiences, including alcohol consumption which has …
relations. Adolescents live new experiences, including alcohol consumption which has …
Nitric oxide donor drugs: an update on pathophysiology and therapeutic potential
The discovery of the multiple physiological and pathophysiological processes in which nitric
oxide (NO) is involved has promoted a great number of pharmacological researches to …
oxide (NO) is involved has promoted a great number of pharmacological researches to …
Role of nitric oxide in cerebellar development and function: focus on granule neurons
A Contestabile - The Cerebellum, 2012 - Springer
More than 20 years of research have firmly established important roles of the diffusible
messenger molecule, nitric oxide (NO), in cerebellar development and function. Granule …
messenger molecule, nitric oxide (NO), in cerebellar development and function. Granule …
PFOS-induced excitotoxicity is dependent on Ca2+ influx via NMDA receptors in rat cerebellar granule neurons
HF Berntsen, CG Bjørklund, R Strandabø… - Toxicology and applied …, 2018 - Elsevier
Perfluoroalkyl acids (PFAAs) are persistent compounds used in many industrial as well as
consumer products. Despite restrictions, these compounds are found at measurable …
consumer products. Despite restrictions, these compounds are found at measurable …
Targeting nitric oxide with drug therapy
RP Mason, JR Cockcroft - The Journal of Clinical Hypertension, 2006 - Wiley Online Library
Increasing knowledge of the role of nitric oxide (NO) in physiology and disease has
stimulated efforts to target the NO pathway pharmacologically. These therapeutic strategies …
stimulated efforts to target the NO pathway pharmacologically. These therapeutic strategies …