A modified Bayes information criterion with applications to the analysis of comparative genomic hybridization data
NR Zhang, DO Siegmund - Biometrics, 2007 - academic.oup.com
In the analysis of data generated by change-point processes, one critical challenge is to
determine the number of change-points. The classic Bayes information criterion (BIC) …
determine the number of change-points. The classic Bayes information criterion (BIC) …
Comparative analysis of algorithms for identifying amplifications and deletions in array CGH data
WR Lai, MD Johnson, R Kucherlapati, PJ Park - Bioinformatics, 2005 - academic.oup.com
Abstract Motivation: Array Comparative Genomic Hybridization (CGH) can reveal
chromosomal aberrations in the genomic DNA. These amplifications and deletions at the …
chromosomal aberrations in the genomic DNA. These amplifications and deletions at the …
A comparison study: applying segmentation to array CGH data for downstream analyses
H Willenbrock, J Fridlyand - Bioinformatics, 2005 - academic.oup.com
Motivation: Array comparative genomic hybridization (CGH) allows detection and mapping
of copy number of DNA segments. A challenge is to make inferences about the copy number …
of copy number of DNA segments. A challenge is to make inferences about the copy number …
Methods and processes for non-invasive assessment of genetic variations
2016-05-06 Assigned to SEQUENOM, INC. reassignment SEQUENOM, INC. CORRECTIVE
ASSIGNMENT TO CORRECT THE ASSIGNEE STATE OF INCORPORATION INSIDE THE …
ASSIGNMENT TO CORRECT THE ASSIGNEE STATE OF INCORPORATION INSIDE THE …
Detecting simultaneous changepoints in multiple sequences
We discuss the detection of local signals that occur at the same location in multiple one-
dimensional noisy sequences, with particular attention to relatively weak signals that may …
dimensional noisy sequences, with particular attention to relatively weak signals that may …
Efficient change point detection for genomic sequences of continuous measurements
VMR Muggeo, G Adelfio - Bioinformatics, 2011 - academic.oup.com
Motivation: Knowing the exact locations of multiple change points in genomic sequences
serves several biological needs, for instance when data represent aCGH profiles and it is of …
serves several biological needs, for instance when data represent aCGH profiles and it is of …
A fast Bayesian change point analysis for the segmentation of microarray data
C Erdman, JW Emerson - Bioinformatics, 2008 - academic.oup.com
Motivation: The ability to detect regions of genetic alteration is of great importance in cancer
research. These alterations can take the form of large chromosomal gains and losses as …
research. These alterations can take the form of large chromosomal gains and losses as …
Preprocessing and downstream analysis of microarray DNA copy number profiles
MA Van de Wiel, F Picard… - Briefings in …, 2011 - academic.oup.com
Abstract Analysis of DNA copy number profiles requires methods tailored to the specific
nature of these data. The number of available data analysis methods has grown enormously …
nature of these data. The number of available data analysis methods has grown enormously …
Integrating copy number polymorphisms into array CGH analysis using a robust HMM
SP Shah, X Xuan, RJ DeLeeuw, M Khojasteh… - …, 2006 - academic.oup.com
Motivation: Array comparative genomic hybridization (aCGH) is a pervasive technique used
to identify chromosomal aberrations in human diseases, including cancer. Aberrations are …
to identify chromosomal aberrations in human diseases, including cancer. Aberrations are …
Reducing sequence read count error in assessment of complex genetic variations
BACKGROUND Genetic information of living organisms (eg, animals, plants and
microorganisms) and other forms of replicating genetic information (eg, viruses) is encoded …
microorganisms) and other forms of replicating genetic information (eg, viruses) is encoded …