Towards an integrated understanding of dietary phenotypes
D Raubenheimer, R Hou, Y Dong… - … Transactions of the …, 2023 - royalsocietypublishing.org
Diet and nutrition comprise a complex, multi-faceted interface between animal biology and
food environments. With accumulating information on the many facets of this association …
food environments. With accumulating information on the many facets of this association …
[HTML][HTML] Going beyond established model systems of Alzheimer's disease: companion animals provide novel insights into the neurobiology of aging
AA de Sousa, BA Rigby Dames, EC Graff… - Communications …, 2023 - nature.com
Alzheimer's disease (AD) is characterized by brain plaques, tangles, and cognitive
impairment. AD is one of the most common age-related dementias in humans. Progress in …
impairment. AD is one of the most common age-related dementias in humans. Progress in …
Neural signatures of natural behaviour in socializing macaques
Our understanding of the neurobiology of primate behaviour largely derives from artificial
tasks in highly controlled laboratory settings, overlooking most natural behaviours that …
tasks in highly controlled laboratory settings, overlooking most natural behaviours that …
Ecological disturbance alters the adaptive benefits of social ties
Extreme weather events radically alter ecosystems. When ecological damage persists,
selective pressures on individuals can change, leading to phenotypic adjustments. For …
selective pressures on individuals can change, leading to phenotypic adjustments. For …
[HTML][HTML] An evolutionary model for the ancient origins of polycystic ovary syndrome
DA Dumesic, DH Abbott, GD Chazenbalk - Journal of Clinical Medicine, 2023 - mdpi.com
Polycystic ovary syndrome (PCOS) is a common endocrinopathy of reproductive-aged
women, characterized by hyperandrogenism, oligo-anovulation and insulin resistance and …
women, characterized by hyperandrogenism, oligo-anovulation and insulin resistance and …
The biology of aging in a social world: Insights from free-ranging rhesus macaques
Social adversity can increase the age-associated risk of disease and death, yet the
biological mechanisms that link social adversities to aging remain poorly understood. Long …
biological mechanisms that link social adversities to aging remain poorly understood. Long …
Natural animal populations as model systems for understanding early life adversity effects on aging
Adverse experiences in early life are associated with aging-related disease risk and
mortality across many species. In humans, confounding factors, as well as the difficulty of …
mortality across many species. In humans, confounding factors, as well as the difficulty of …
Geosmin, a Food-and Water-Deteriorating Sesquiterpenoid and Ambivalent Semiochemical, Activates Evolutionary Conserved Receptor OR11A1
L Ball, T Frey, F Haag, S Frank… - Journal of Agricultural …, 2024 - ACS Publications
Geosmin, a ubiquitous volatile sesquiterpenoid of microbiological origin, is causative for
deteriorating the quality of many foods, beverages, and drinking water, by eliciting an …
deteriorating the quality of many foods, beverages, and drinking water, by eliciting an …
[HTML][HTML] Evolutionary and biomedical implications of sex differences in the primate brain transcriptome
Humans exhibit sex differences in the prevalence of many neurodevelopmental disorders
and neurodegenerative diseases. Here, we generated one of the largest multi-brain-region …
and neurodegenerative diseases. Here, we generated one of the largest multi-brain-region …
Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque
X Castro Dopico, M Guryleva… - Clinical & …, 2024 - Wiley Online Library
Objectives The caecum bridges the small and large intestine and plays a front‐line role in
discriminating gastrointestinal antigens. Although dysregulated in acute and chronic …
discriminating gastrointestinal antigens. Although dysregulated in acute and chronic …