[HTML][HTML] Hijacking of the AP-1 signaling pathway during development of ATL

H Gazon, B Barbeau, JM Mesnard… - Frontiers in …, 2018 - frontiersin.org
Human T-cell leukemia virus type 1 (HTLV-1) is the causative agent of a fatal malignancy
known as adult T-cell leukemia (ATL). One way to address the pathology of the disease lies …

Drug repurposing for viral cancers: A paradigm of machine learning, deep learning, and virtual screening‐based approaches

F Ahmed, IS Kang, KH Kim, A Asif… - Journal of Medical …, 2023 - Wiley Online Library
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …

[HTML][HTML] Viral oncology: molecular biology and pathogenesis

UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …

[HTML][HTML] HTLV-1 infection: An emerging risk. Pathogenesis, epidemiology, diagnosis and associated diseases

E Eusebio-Ponce, E Anguita… - Revista Española de …, 2019 - ncbi.nlm.nih.gov
ABSTRACT The Human T-Lymphotropic Virus type 1 (HTLV-1) affects up to 10 million
people worldwide. It is directly associated to one of the most aggressive T cell malignancies …

[HTML][HTML] Mother-to-child HTLV-1 transmission: unmet research needs

C Rosadas, GP Taylor - Frontiers in microbiology, 2019 - frontiersin.org
Mother-to-child transmission (MTCT) of Human T-cell lymphotropic virus type 1 (HTLV-1)
causes lifelong infection. At least 5–10 million individuals worldwide are currently living with …

[HTML][HTML] Mechanisms of oncogenesis by HTLV-1 Tax

S Mohanty, EW Harhaj - Pathogens, 2020 - mdpi.com
The human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T-cell
leukemia/lymphoma (ATLL), a neoplasm of CD4+ CD25+ T cells that occurs in 2–5% of …

[HTML][HTML] HTLV-1, the other pathogenic yet neglected human retrovirus: from transmission to therapeutic treatment

N Futsch, R Mahieux, H Dutartre - Viruses, 2017 - mdpi.com
Going back to their discovery in the early 1980s, both the Human T-cell Leukemia virus type-
1 (HTLV-1) and the Human Immunodeficiency Virus type-1 (HIV-1) greatly fascinated the …

Reducing the global burden of HTLV-1 infection: an agenda for research and action

L Willems, H Hasegawa, R Accolla, C Bangham… - Antiviral research, 2017 - Elsevier
Even though an estimated 10–20 million people worldwide are infected with the oncogenic
retrovirus, human T-lymphotropic virus type 1 (HTLV-1), its epidemiology is poorly …

[HTML][HTML] Molecular mechanisms of HTLV-1 cell-to-cell transmission

C Gross, AK Thoma-Kress - Viruses, 2016 - mdpi.com
The tumorvirus human T-cell lymphotropic virus type 1 (HTLV-1), a member of the delta-
retrovirus family, is transmitted via cell-containing body fluids such as blood products …

Stability analysis of fuzzy HTLV-I infection model: a dynamic approach

S Bera, S Khajanchi, TK Roy - Journal of Applied Mathematics and …, 2023 - Springer
This paper deals with a mathematical model for HTLV-I infection by considering the role of
imprecise essence of the biological parameters. The considered imprecise biologically …