Past, present and (foreseeable) future of biological anti-TNF alpha therapy

GM Leone, K Mangano, MC Petralia, F Nicoletti… - Journal of Clinical …, 2023 - mdpi.com
Due to the key role of tumor necrosis factor-alpha (TNF-α) in the pathogenesis of
immunoinflammatory diseases, TNF-α inhibitors have been successfully developed and …

Expert consensus on the systemic treatment of atopic dermatitis in special populations

DN Adam, MJ Gooderham, JR Beecker… - Journal of the …, 2023 - Wiley Online Library
With the increasing number of options for the treatment of moderate‐to‐severe atopic
dermatitis, clinicians need guidance on a practical approach to selecting a systemic agent …

European Crohn's and colitis guidelines on sexuality, fertility, pregnancy, and lactation

J Torres, M Chaparro, M Julsgaard… - Journal of Crohn's …, 2023 - academic.oup.com
2. Methods This document represents the third version of the European Consensus on
reproduction in IBD. The development of this Consensus included the formulation of …

GDF15 linked to maternal risk of nausea and vomiting during pregnancy

M Fejzo, N Rocha, I Cimino, SM Lockhart, CJ Petry… - Nature, 2024 - nature.com
GDF15, a hormone acting on the brainstem, has been implicated in the nausea and vomiting
of pregnancy, including its most severe form, hyperemesis gravidarum (HG), but a full …

Reversing the Inflammatory Process—25 Years of Tumor Necrosis Factor-α Inhibitors

KN Muth, J Rech, FO Losch, A Hoerning - Journal of Clinical Medicine, 2023 - mdpi.com
Immune-mediated inflammatory diseases, such as rheumatoid arthritis, psoriatic arthritis,
peripheral and/or axial spondyloarthritis, Crohn's disease, and ulcerative colitis, are …

[PDF][PDF] Safety profile of Dupilumab during pregnancy: a data mining and disproportionality analysis of over 37,000 reports from the WHO individual case safety …

R Khamisy-Farah, G Damiani, JD Kong… - Eur Rev Med …, 2021 - researchgate.net
Atopic dermatitis, known also as atopic eczema, represents a commonly diagnosed, chronic
or recurrent/relapsing inflammatory disorder. From a clinical point of view, it is characterized …

Therapeutical targets in allergic inflammation

L Salvati, F Liotta, F Annunziato, L Cosmi - Biomedicines, 2022 - mdpi.com
From the discovery of IgE to the in-depth characterization of Th2 cells and ILC2, allergic
inflammation has been extensively addressed to find potential therapeutical targets. To date …

Characteristic analysis of adverse reactions of five anti-TNFɑ agents: a descriptive analysis from WHO-VigiAccess

M Li, R You, Y Su, H Zhou, S Gong - Frontiers in Pharmacology, 2023 - frontiersin.org
Introduction: Tumor necrosis factor (TNF) inhibitors (adalimumab, infliximab, etanercept,
golimumab, and certolizumab pegol) have revolutionized the treatment of severe immune …

Beyond systemic lupus erythematosus and anti-phospholipid syndrome: the relevance of complement from pathogenesis to pregnancy outcome in other systemic …

S Cavalli, PA Lonati, M Gerosa, R Caporali… - Frontiers in …, 2022 - frontiersin.org
Evidence about the relevance of the complement system, a highly conserved constituent of
the innate immunity response that orchestrates the elimination of pathogens and the …

[HTML][HTML] Clinical considerations in the management of hidradenitis suppurativa in women

EK Kozera, MA Lowes, JL Hsiao, JW Frew - International Journal of …, 2021 - Elsevier
Hidradenitis suppurativa (HS) is a chronic, inflammatory disease of the skin with a
predilection for women. The role of sex hormones, including estrogen and progesterone, is …