Liver natural killer and natural killer T cells not only play a critical role in anti–viral and anti–
tumor defenses but also contribute to the pathogenesis of chronic liver diseases. Hepatic …

Natural killer T (NKT) cells are innate-like lymphocytes that generally recognize lipid
antigens and are enriched in microvascular compartments of the liver. NKT cells can be …

Introduction• Gene structure and regulation• Target molecules• Role in development• Role in
cancer• Other biological functions• Summary and perspectives The discovery of microRNAs …

Toll-like receptor 3 (TLR3) plays a critical role in initiating type I IFN-mediated innate
immunity against viral infections. TLR3 recognizes various forms of double stranded (ds) …

CD8+ T cells are activated by TCRs that recognize specific cognate Ags, while NK-cell
activation is regulated by a balance between signals from germline-encoded activating and …

Background & Aims The liver provides a unique niche of lymphocytes enriched with a large
proportion of innate-like T cells. However, the heterogeneity and functional characteristics of …

In order to investigate the global and dynamic host microRNAs (miRNAs)/messenger RNAs
(mRNAs) expression alteration during in vitro acute HCV infection, a comprehensive …

CD56pos natural killer (NK)/natural T (NT) cells are important innate effectors providing the
first line of defense against viral infection. Enhanced NK activity has been shown to protect …

Exosomes are a class of cell-released small vesicles that mediate intercellular
communication by delivering functional factors to recipient cells. During hepatitis C virus …

Primary hepatocytes (PH) have been widely used in metabolic and disease-resistance
mechanism research. However, hepatocyte isolation (HI) remains challenging in ducks. This …