Geroscience, an emerging discipline at the intersection of aging and disease, seeks to
understand the relationship between the aging process and pathogenesis of age-related …

Dysregulation of mitochondrial homeostasis is common to all types of cardiovascular
diseases. SIRT3 regulates apoptosis and autophagy, material and energy metabolism …

Background Diabetes is associated with an increased risk of cognitive decline and
dementia. These diseases are linked with mitochondrial dysfunction, most likely as a …

Oxidative stress and impaired mitophagy are the hallmarks of cardiomyocyte senescence.
Specifically, a decrease in mitophagic flux leads to the accumulation of damaged …

Background Phosphofructo‐2‐kinase/fructose‐2, 6‐bisphosphatase (PFK‐2) is a critical
glycolytic regulator responsible for upregulation of glycolysis in response to insulin and …

Background Postresuscitation cardiac dysfunction is a significant contributor to early death
following cardiopulmonary resuscitation (CPR). Therapeutic hypothermia (TH) mitigates …

Abstract Whether miR-29a-5p is associated with diabetic retinopathy (DR) is still a subject of
ongoing discussion. The current research examines the involvement of miR-29a-5p in …