[HTML][HTML] Lipid droplet biogenesis and functions in health and disease

A Zadoorian, X Du, H Yang - Nature Reviews Endocrinology, 2023 - nature.com
Ubiquitous yet unique, lipid droplets are intracellular organelles that are increasingly being
recognized for their versatility beyond energy storage. Advances uncovering the intricacies …

[HTML][HTML] Redox biology of respiratory viral infections

OA Khomich, SN Kochetkov, B Bartosch, AV Ivanov - Viruses, 2018 - mdpi.com
Respiratory viruses cause infections of the upper or lower respiratory tract and they are
responsible for the common cold—the most prevalent disease in the world. In many cases …

[PDF][PDF] Ribosome collisions trigger general stress responses to regulate cell fate

CCC Wu, A Peterson, B Zinshteyn, S Regot, R Green - Cell, 2020 - cell.com
Problems arising during translation of mRNAs lead to ribosome stalling and collisions that
trigger a series of quality control events. However, the global cellular response to ribosome …

[HTML][HTML] Invited review: Inflammation during the transition to lactation: New adventures with an old flame

BJ Bradford, K Yuan, JK Farney, LK Mamedova… - Journal of dairy …, 2015 - Elsevier
For dairy cattle, the first several weeks of lactation represent the highest-risk period in their
lives after their own neonatal period. Although more than 50% of cows during this period are …

Mechanistic insight of diabetic nephropathy and its pharmacotherapeutic targets: an update

N Bhattacharjee, S Barma, N Konwar… - European journal of …, 2016 - Elsevier
Diabetic nephropathy (DN), a chronic complication of diabetes, is charecterized by
glomerular hypertrophy, proteinuria, decreased glomerular filtration, and renal fibrosis …

[HTML][HTML] Transcription factor C/EBP homologous protein in health and diseases

Y Yang, L Liu, I Naik, Z Braunstein, J Zhong… - Frontiers in …, 2017 - frontiersin.org
C/EBP homologous protein (CHOP), known also as DNA damage-inducible transcript 3 and
as growth arrest and DNA damage-inducible protein 153 (GADD153), is induced in …

[HTML][HTML] Endoplasmic reticulum stress in metabolic liver diseases and hepatic fibrosis

JL Maiers, H Malhi - Seminars in liver disease, 2019 - thieme-connect.com
Endoplasmic reticulum (ER) stress is a major contributor to liver disease and hepatic
fibrosis, but the role it plays varies depending on the cause and progression of the disease …

[HTML][HTML] SNHG12: an LncRNA as a potential therapeutic target and biomarker for human cancer

S Tamang, V Acharya, D Roy, R Sharma… - Frontiers in …, 2019 - frontiersin.org
Limitations in current diagnostic procedures warrant identification of new methodologies to
improve diagnoses of cancer patients. In this context, long non-coding RNAs (lncRNAs) …

Beyond the cell factory: Homeostatic regulation of and by the UPRER

MG Metcalf, R Higuchi-Sanabria, G Garcia, CK Tsui… - Science …, 2020 - science.org
The endoplasmic reticulum (ER) is commonly referred to as the factory of the cell, as it is
responsible for a large amount of protein and lipid synthesis. As a membrane-bound …

ER stress activates the NLRP3 inflammasome: a novel mechanism of atherosclerosis

X Chen, X Guo, Q Ge, Y Zhao, H Mu… - Oxidative Medicine and …, 2019 - Wiley Online Library
The endoplasmic reticulum (ER) is an important organelle that regulates several
fundamental cellular processes, and ER dysfunction has implications for many intracellular …