The involvement of long non-coding RNAs in bone
C Aurilia, S Donati, G Palmini, F Miglietta… - International journal of …, 2021 - mdpi.com
A harmonious balance between osteoblast and osteoclast activity guarantees optimal bone
formation and resorption, pathological conditions affecting the bone may arise. In recent …
formation and resorption, pathological conditions affecting the bone may arise. In recent …
LncRNAs as a new regulator of chronic musculoskeletal disorder
H Huang, D Xing, Q Zhang, H Li, J Lin, Z He… - Cell …, 2021 - Wiley Online Library
Objectives In recent years, long non‐coding RNAs (lncRNAs) have been found to play a role
in the occurrence, progression and prognosis of chronic musculoskeletal disorders. Design …
in the occurrence, progression and prognosis of chronic musculoskeletal disorders. Design …
Bone marrow mesenchymal stem cells derived exosomal Lnc TUG1 promotes bone fracture recovery via miR-22-5p/Anxa8 axis
W Li, L Li, R Cui, X Chen, H Hu, Y Qiu - Human Cell, 2023 - Springer
Bone fracture healing is a complex physiologic process that involves changes in the
expression of several thousand genes. Long noncoding RNAs (lncRNAs) may have critical …
expression of several thousand genes. Long noncoding RNAs (lncRNAs) may have critical …
Epigenetic therapy targeting bone marrow mesenchymal stem cells for age-related bone diseases
Y Zhao, J He, T Qiu, H Zhang, L Liao, X Su - Stem cell research & therapy, 2022 - Springer
As global aging accelerates, the prevention and treatment of age-related bone diseases are
becoming a critical issue. In the process of senescence, bone marrow mesenchymal stem …
becoming a critical issue. In the process of senescence, bone marrow mesenchymal stem …
Systematic analysis of mRNAs and ncRNAs in BMSCs of senile osteoporosis patients
Y Geng, J Chen, C Chang, Y Zhang, L Duan… - Frontiers in …, 2021 - frontiersin.org
Senile osteoporosis (SOP) is a worldwide age-related disease characterized by the loss of
bone mass and decrease in bone strength. Bone mesenchymal stem cells (BMSCs) play an …
bone mass and decrease in bone strength. Bone mesenchymal stem cells (BMSCs) play an …
lncRNA PAPPA‐AS1 induces the development of hypertrophic scar by upregulating TLR4 through interacting with TAF15
P Fan, Y Wang, J Li, M Fang - Mediators of Inflammation, 2021 - Wiley Online Library
Hypertrophic scar (HTS) is a complicated pathological process induced mainly by burns and
wounds, with abnormal proliferation of fibroblasts and the transformation of fibroblasts to …
wounds, with abnormal proliferation of fibroblasts and the transformation of fibroblasts to …
Long non‑coding RNA RP11‑84C13. 1 promotes osteogenic differentiation of bone mesenchymal stem cells and alleviates osteoporosis progression via the miR‑23b …
H Yu, Y Li, J Tang, X Lu, W Hu… - Experimental and …, 2021 - spandidos-publications.com
The objective of the present study was to determine the role of RP11‑84C13. 1 in
osteoporosis (OP) and its molecular mechanism. First, clinical samples were collected from …
osteoporosis (OP) and its molecular mechanism. First, clinical samples were collected from …
LncRNA HOTAIRM1 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells by targeting miR-152-3p/ETS1 axis
X Wang, Y Liu, P Lei - Molecular Biology Reports, 2023 - Springer
Background Bone marrow mesenchymal stem cells (BMSCs) can differentiate into
osteoblasts and thus present a tremendous therapeutic potential in osteoporosis. Here, we …
osteoblasts and thus present a tremendous therapeutic potential in osteoporosis. Here, we …
Epigenetic therapies of osteoporosis
The study of epigenetics reaches its 50th anniversary, however, its clinical application is
gradually coming into the clinical setting. Osteoporosis is one of the major and widely …
gradually coming into the clinical setting. Osteoporosis is one of the major and widely …
LINC01234 Sponging of the miR-513a-5p/AOX1 Axis is Upregulated in Osteoporosis and Regulates Osteogenic Differentiation of Bone Marrow Mesenchymal Stem …
Z Yan, Q He - Molecular Biotechnology, 2023 - Springer
Non-coding RNAs, including long-chain non-coding RNA (lncRNA) and micro-RNA
(miRNA), have been implicated in osteoporosis (OP) progression by regulating osteoblast …
(miRNA), have been implicated in osteoporosis (OP) progression by regulating osteoblast …