Growing evidences suggest that the fibroblast growth factor/FGF receptor (FGF/FGFR)
signaling has crucial roles in a multitude of processes during embryonic development and …

Regulated fibroblast growth factor (FGF) signalling is a prerequisite for the correct
development and homeostasis of articular cartilage, as evidenced by the fact that aberrant …

The fibroblast growth factor (FGF) family is composed of 18 secreted signaling proteins
consisting of canonical FGFs and endocrine FGFs that activate four receptor tyrosine …

In 1993, Jabs et al. were the first to describe a genetic origin of craniosynostosis. Since this
discovery, the genetic causes of the most common syndromes have been described. In …

Suture mesenchymal stem cells (SMSCs) are a heterogeneous stem cell population with the
ability to self-renew and differentiate into multiple cell lineages. The cranial suture provides …

Fibroblast growth factor (FGF) signaling pathways have well‐established roles in skeletal
development, with essential functions in both chondrogenesis and osteogenesis. In mice …

Craniosynostosis, the premature fusion of the cranial sutures, affects~ 1 in 2000 children.
Although many patients with a genetically determined cause harbor a variant in one of just …

Abstract 46, XY gonadal dysgenesis (GD) is a Disorder/Difference of Sex Development
(DSD) that can present with phenotypes ranging from ambiguous genitalia to complete male …

Cleft palate, a common global congenital malformation, occurs due to disturbances in
palatal growth, elevation, contact, and fusion during palatogenesis. The Fibroblast growth …

Multiple synostoses syndrome (OMIM:# 186500,# 610017,# 612961,# 617898) is a
genetically heterogeneous group of autosomal dominant diseases characterized by …