Beyond macromolecules: extracellular vesicles as regulators of inflammatory diseases

K Das, S Paul, T Mukherjee, A Ghosh, A Sharma… - Cells, 2023 - mdpi.com
Inflammation is the defense mechanism of the immune system against harmful stimuli such
as pathogens, toxic compounds, damaged cells, radiation, etc., and is characterized by …

Plasma-derived exosomal miRNA as potential biomarker for diagnosis and prognosis of vector-borne diseases: A review

G Venkatesan, WS Wan Ab Rahman… - Frontiers in …, 2023 - frontiersin.org
Early disease diagnosis is critical for better management and treatment outcome of patients.
Therefore, diagnostic methods should ideally be accurate, consistent, easy to perform at low …

Double-Stranded RNA Viruses Are Released From Trichomonas vaginalis Inside Small Extracellular Vesicles and Modulate the Exosomal Cargo

P Rada, I Hrdý, A Zdrha, RK Narayanasamy… - Frontiers in …, 2022 - frontiersin.org
Trichomonas vaginalis is a parasitic protist that infects the human urogenital tract. During the
infection, trichomonads adhere to the host mucosa, acquire nutrients from the …

Extracellular Vesicles Derived from Early and Late Stage Plasmodium falciparum-Infected Red Blood Cells Contain Invasion-Associated Proteins

S Vimonpatranon, S Roytrakul, N Phaonakrop… - Journal of Clinical …, 2022 - mdpi.com
In infectious diseases, extracellular vesicles (EVs) released from a pathogen or pathogen-
infected cells can transfer pathogen-derived biomolecules, especially proteins, to target cells …

Nanocarrier based active targeting strategies against erythrocytic stage of malaria

AR Bhide, DH Surve, AB Jindal - Journal of Controlled Release, 2023 - Elsevier
Abstract The Global Technical Strategy for Malaria 2016–2030 aims to achieve a 90%
reduction in malaria cases, and strategic planning and execution are crucial for …

Protein profiling of malaria-derived extracellular vesicles reveals distinct subtypes

T Opadokun, J Agyapong, P Rohrbach - Membranes, 2022 - mdpi.com
Malaria is caused by obligate intracellular parasites belonging to the genus Plasmodium.
Red blood cells (RBCs) infected with different stages of Plasmodium spp. release …

Erythropoiesis and malaria, a multifaceted interplay

A Dumarchey, C Lavazec, F Verdier - International Journal of Molecular …, 2022 - mdpi.com
One of the major pathophysiologies of malaria is the development of anemia. Although
hemolysis and splenic clearance are well described as causes of malarial anemia …

Malaria-derived exosomes exacerbate liver injury during blood stage of Plasmodium berghei infection

X Zhang, M Zhang, QR Wang, X Hou, T Zhou, J Liu… - Acta Tropica, 2023 - Elsevier
Liver injury is a common clinical feature of Plasmodium spp. infection and contributes to
multi-organ failure of severe malaria. Malaria-derived exosomes (MD-Exos) have recently …

[HTML][HTML] Identification and characterization of extracellular vesicles from red cells infected with Babesia divergens and Babesia microti

D Beri, M Rodriguez, M Singh, Y Liu… - Frontiers in Cellular …, 2022 - frontiersin.org
Babesiosis is a zoonosis and an important blood-borne human parasitic infection, that has
gained attention because of its growing infection rate in humans by transfer from animal …

An in-depth exploration of the multifaceted roles of EVs in the context of pathogenic single-cell microorganisms

AS Feix, EZ Tabaie, AN Singh… - Microbiology and …, 2024 - Am Soc Microbiol
Extracellular vesicles (EVs) have been recognized throughout scientific communities as
potential vehicles of intercellular communication in both eukaryotes and prokaryotes …