Exposure to particulate silica (most crystalline polymorphs) causes a persistent inflammation
sustained by the release of oxidants in the alveolar space. Reactive oxygen species (ROS) …

Further research on the molecular mechanisms involved in the inflammatory processes
important for progression to fibrotic diseases is needed for the development of effective …

Firefighting, along with construction, mining and agriculture, ranks among the most
dangerous occupations. In addition, the work environment of firefighters is unlike that of any …

The study investigated the reversal of multidrug resistance (MDR) and the biodistribution of
nanoparticles (NPs) that target leukemia cells in a nude mice model via a surface-bound …

Stroke is one of the leading causes of mortality, with a high incidence of severe morbidity in
survivors. The treatment to minimize tissue injury after stroke is still unsatisfactory and it is …

Objectives To investigate the influence of the anti-tumor necrosis factor-α infliximab (IFX) in
the case of rats with silicosis. Material and Methods Forty-eight Wistar rats were randomly …

Exposure to crystalline silica can result in damage to the lung parenchyma and scarring that
can lead to fibrosis. Pulmonary damage may be the direct consequence of toxic interaction …

The scavenging and iron-reducing properties of a series of benzylisoquinolines of natural
and synthetic origin have been studied. Bulbocapnine, boldine, glaucine, and stepholidine …

In vivo exposure of rat lungs to crystalline silica either by intratracheal instillation or by
inhalation results in an increase in mRNA levels for inducible nitric oxide synthase (iNOS) in …

This study investigated the effect of tetrandrine (TDR) on ex-perimental herpes simplex
keratitis (HSK) in mice. BALB/c mice were di-vided as follows: Group I, untreated; Group 2 …