MicroRNAs are a class of reliable biomarkers for noninvasive detection of a variety of
diseases, including cancers. This is because miRNA, especially exosome miRNAs, can …

Advanced studies of microRNAs (miRNAs) have revealed their manifold biological functions,
including control of cell proliferation, cell cycle and cell death. However, it seems that their …

Purpose: PARP inhibitors (PARPi) are primarily effective against BRCA1/2-mutated breast
and ovarian cancers, but resistance due to reversion of mutated BRCA1/2 and other …

Background MicroRNAs (miRNAs) are short, non-coding RNA molecules that act as
regulators of gene expression. Circulating blood miRNAs offer great potential as cancer …

Patients with primary HER2-positive breast cancer benefit from HER2-targeted therapies.
Nevertheless, a significant proportion of these patients die of disease progression due to …

Small noncoding microRNAs (miRNAs) are important regulators of post-transcriptional gene
regulation and have altered the prevailing view of a linear relationship between gene and …

Colorectal cancer (CRC) is one of the most common cancers and a leading cause of cancer-
related deaths worldwide. Despite numerous advances in therapeutic approaches, this …

Temozolomide (TMZ) is the most commonly used alkylating agent in glioma chemotherapy.
However, growing resistance to TMZ remains a major challenge for clinicians. Recent …

An increasing body of evidence suggests that cancer cells acquire “stem‐like” epigenetic
and signaling characteristics during the tumorigenic process, including global DNA hypo …

Since they were first described in the 1990s, circulating microRNAs (miRNAs) have provided
an active and rapidly evolving area of current research that has the potential to transform …