White matter damage quantified as white matter hyperintensities (WMH) may aggravate
cognitive and motor impairments, but whether and how WMH burden impacts these …

Cerebral small vessel disease (CSVD) results in a spectrum of neurologic, behavioral, and
cognitive sequelae, most commonly from white matter hyperintensities (WMH) of presumed …

Background The trialed treatment landscape of Parkinson's disease (PD) is extensive, but
up to now, there is no disease-modifying therapy. As the pathophysiology of PD becomes …

Background To investigate whether structural network disconnectivity is associated with
parkinsonian signs and their progression, as well as with an increased risk of incident …

Cerebral small vessel disease (SVD) is known to contribute to cognitive impairment, apathy,
and gait dysfunction. Although associations between cognitive impairment and either apathy …

Background The effects of individual panaxadiol saponin and panaxatriol saponin on rodent
models of Parkinson's disease (PD) have been recognized. However, it is not clear whether …

Background and Objectives Patients with cerebral small vessel disease (SVD) show a
heterogenous clinical course. The aim of the current study was to investigate the longitudinal …

We review the epidemiologic literature on potential protective and risk factors in Parkinson's
Disease (PD). Prior research identified numerous possible protective and risk factors …

Background Although acquired dystonia may develop following ischaemic/haemorrhagic
stroke, the relationship between cerebrovascular disease and idiopathic dystonia has been …