Isoliquiritigenin, a potential therapeutic agent for treatment of inflammation-associated diseases

Z Chen, W Ding, X Yang, T Lu, Y Liu - Journal of ethnopharmacology, 2023 - Elsevier
Ethnopharmacological relevance Licorice is a medicinal herb with a 2000-year history of
applications in traditional Chinese medicine. Isoliquiritigenin (ISL) is a bioactive chalcone …

Recent Advances in Glycyrrhiza glabra (Licorice)-Containing Herbs Alleviating Radiotherapy- and Chemotherapy-Induced Adverse Reactions in Cancer Treatment

KL Wang, YC Yu, HY Chen, YF Chiang, M Ali… - Metabolites, 2022 - mdpi.com
Cancers represent a significant cause of morbidity and mortality worldwide. They also
impose a large economic burden on patients, their families, and health insurance systems …

Hederagenin Suppresses Inflammation and Cartilage Degradation to Ameliorate the Progression of Osteoarthritis: An In vivo and In vitro Study

Y Shen, L Teng, Y Qu, Y Huang, Y Peng, M Tang, Q Fu - Inflammation, 2023 - Springer
Osteoarthritis (OA), a common degenerative joint disease, is characterized by the
progressive degradation of articular cartilage and inflammation. Hederagenin (HE) is a …

[HTML][HTML] Tiao-bu-fei-shen formula promotes downregulation of the caveolin 1-p38 mapk signaling pathway in COPD-associated tracheobronchomalacia cell model

P Zhou, W Yu, C Zhang, K Chen, W Tang, X Li… - Journal of …, 2022 - Elsevier
Abstract Ethnopharmacological relevance The Tiao-bu-fei-shen (TBFS) formula, extensively
used in Traditional Chinese Medicine (TCM), can enhance therapeutic efficacy and reduce …

Protein phosphatase 2A modulation and connection with miRNAs and natural products

YT Chuang, CY Yen, JY Tang, FR Chang… - Environmental …, 2024 - Wiley Online Library
Abstract Protein phosphatase 2A (PP2A), a heterotrimeric holoenzyme (scaffolding, catalytic,
and regulatory subunits), regulates dephosphorylation for more than half of serine/threonine …

Whole-Transcriptome Sequencing of Knee Joint Cartilage from Kashin–Beck Disease and Osteoarthritis Patients

L Han, B Cheng, W Wei, L Liu, S Cheng, H Liu… - International Journal of …, 2024 - mdpi.com
The aim of this study was to provide a comprehensive understanding of similarities and
differences in mRNAs, lncRNAs, and circRNAs within cartilage for Kashin–Beck disease …

Gentiopicroside ameliorates the lipopolysaccharide-induced inflammatory response and hypertrophy in chondrocytes

L Li, Q Fan, Y Zhao, Q Zhang, G Qin, C Li… - Journal of Orthopaedic …, 2024 - Springer
Purpose This study aimed to evaluate the protective effects of gentiopicroside against
lipopolysaccharide-induced chondrocyte inflammation. Methods SW 1353 chondrosarcoma …

Decipher the action mechanism of Simiao Pill in the treatment of knee osteoarthritis by integrating network pharmacology

M Cheng, M Hong, F Hu, W Liu - Journal of Herbal Medicine, 2023 - Elsevier
Abstract Introduction To explore the Simiao Pill's mode of action in the treatment of knee
osteoarthritis (KOA) by integrating network pharmacology. Methods The Traditional Chinese …

Protective Effect of Glycyrrhiza New Domestic Variety on the Acute Pancreatitis

DG Kim, KH Min - Korean Journal of Plant Resources, 2023 - koreascience.kr
Abstract Glycyrrhiza korshinskyi Grig.(Gk), which is a new variety of Glycyrrhiza, was
developed by the National Institute of Horticultural and Herbal Science in Korea Rural …

Gentiopicroside improves the lipopolysaccharide-induced inflammatory response and hypertrophy in chondrocytes

L Li, Q Fan, Y Zhao, Q Zhang, G Qin, C Li, W Li - 2023 - researchsquare.com
Purpose: This study aimed to evaluate the protective effects of gentiopicroside against
lipopolysaccharide (LPS)-induced chondrocyte inflammation. Methods: Chondrocytes were …