Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions

AH Morris, B Stagg, M Lanspa, J Orme… - Journal of the …, 2021 - academic.oup.com
Clinical decision-making is based on knowledge, expertise, and authority, with clinicians
approving almost every intervention—the starting point for delivery of “All the right care, but …

[HTML][HTML] Liberal glucose targets for critically ill diabetic patients: is it time for large clinical trials with more personalized endpoints?

J Jacobi - Annals of Translational Medicine, 2016 - ncbi.nlm.nih.gov
The field of glycemic control for critical care patients has evolved progressively since the
publication of the guidelines for the use of insulin infusions in critically ill patients (1). At that …

A methodology to compare insulin dosing recommendations in real-life settings

D Groat, MA Grando, B Thompson… - Journal of Diabetes …, 2017 - journals.sagepub.com
Background: We propose a methodology to analyze complex real-life glucose data in insulin
pump users. Methods: Patients with type 1 diabetes (T1D) on insulin pumps were recruited …

Metaheuristics for Discovering Favourable Continuous Intravenous Insulin Rate Protocols from Historical Patient Data

H Wang, L Chepulis, RG Paul, M Mayo - … 23–26, 2020, Proceedings, Part I …, 2020 - Springer
Metaheuristic search algorithms such as particle swarm optimisation algorithm and
covariance matrix adaptation evolution strategy are used to discover improved strategies for …

Metaheuristic Optimization of Insulin Infusion Protocols Using Historical Data with Validation Using a Patient Simulator

H Wang, L Chepulis, RG Paul… - Vietnam Journal of …, 2021 - World Scientific
Metaheuristic search algorithms are used to develop new protocols for optimal intravenous
insulin infusion rate recommendations in scenarios involving hospital in-patients with Type 1 …

[PDF][PDF] Model-based decision support for nutrition and insulin treatment of hyperglycaemia in the ICU

ML Rousing - 2017 - vbn.aau.dk
Stress-induced hyperglycaemia commonly occurs during critical illness and has been
associated with increased morbidity and mortality. The results in the literature concerning …

iDECIDE: An Evidence-based Decision Support System for Improving Postprandial Blood Glucose by Accounting for Patient's Preferences

D Groat - 2017 - keep.lib.asu.edu
ABSTRACT Type 1 diabetes (T1D) is a chronic disease that affects 1.25 million people in the
United States. There is no known cure and patients must self-manage the disease to avoid …