Complexes of RNA and cationic peptides for transfection and for immunostimulation
M Fotin-Mleczek, P Baumhof - US Patent 10,111,967, 2018 - Google Patents
US10111967B2 - Complexes of RNA and cationic peptides for transfection and for
immunostimulation - Google Patents US10111967B2 - Complexes of RNA and cationic peptides …
immunostimulation - Google Patents US10111967B2 - Complexes of RNA and cationic peptides …
Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant
M Fotin-Mleczek, R Heidenreich - US Patent 10,369,216, 2019 - Google Patents
The present invention is directed to a polymeric carrier cargo complex, comprising as a
cargo at least one nucleic acid molecule and as a preferably non-toxic and non …
cargo at least one nucleic acid molecule and as a preferably non-toxic and non …
Packaging of immunostimulatory substances into virus-like particles: method of preparation and use
MF Bachmann, T Storni, P Maurer, A Tissot, K Schwarz… - 2003 - Google Patents
Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL
TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL …
TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL …
Method of inducing an antigen-specific immune response by administering a synergistic combination of adjuvants comprising unmethylated CpG-containing nucleic …
HL Davis, J Schorr, AM Krieg - US Patent 7,488,490, 2009 - Google Patents
The present invention relates generally to adjuvants, and in particular to methods and
products utilizing a synergistic combination of immunostimulatory oligonucleotides having at …
products utilizing a synergistic combination of immunostimulatory oligonucleotides having at …
Immunostimulatory nucleic acid molecules
AM Krieg, D Klinman, AD Steinberg - US Patent 7,674,777, 2010 - Google Patents
Nucleic acids containing unmethylated CpG dinucleotides and therapeutic utilities based on
their ability to stimulate an immune response and to redirect a Th2 response to a Th1 …
their ability to stimulate an immune response and to redirect a Th2 response to a Th1 …
Spherical nucleic acid-based constructs as immunostimulatory agents for prophylactic and therapeutic use
AF Radovic-Moreno, CC Mader, S Nallagatla… - US Patent …, 2021 - Google Patents
Aspects of the invention relate to spherical nucleic acid based constructs and related
methods and compositions thereof. The compositions of the invention are useful for …
methods and compositions thereof. The compositions of the invention are useful for …
Methods and products related to treatment and prevention of hepatitis C virus infection
NK Ahluwalia, SM Efler, HL Davis, J Vollmer - US Patent 7,998,492, 2011 - Google Patents
US7998492B2 - Methods and products related to treatment and prevention of hepatitis C virus
infection - Google Patents US7998492B2 - Methods and products related to treatment and …
infection - Google Patents US7998492B2 - Methods and products related to treatment and …
Immunomodulatory oligonucleotides
A Krieg, D Klinman, A Steinberg - US Patent App. 10/769,626, 2004 - Google Patents
Oligonucleotides containing unthylated CpG dinucleotides and therapeutic utilities based on
their ability to Stimulate an immune response in a Subject are disclosed. Also disclosed are …
their ability to Stimulate an immune response in a Subject are disclosed. Also disclosed are …
Methods of using nucleic acid vector-lipid complexes
SW Dow, RE Elmslie, JKJ Schwarze… - US Patent …, 2010 - Google Patents
Related US Application Data (63) Continuation of application No. 10/012,597, filed on Nov.
30, 2001, now abandoned, which is a continua tion-in-part of application No. 09/104,759 …
30, 2001, now abandoned, which is a continua tion-in-part of application No. 09/104,759 …
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
P Baumhof, T Schlake - US Patent 9,907,862, 2018 - Google Patents
A61K47/50—Medicinal preparations characterised by the non-active ingredients used, eg
carriers or inert additives; Targeting or modifying agents chemically bound to the active …
carriers or inert additives; Targeting or modifying agents chemically bound to the active …