Extracellular vesicles as biomarkers in liver diseases: a clinician's point of view

S Thietart, PE Rautou - Journal of hepatology, 2020 - Elsevier
Extracellular vesicles are membrane-bound vesicles containing proteins, lipids, RNAs and
microRNAs. They can originate from both healthy and stressed cells, and provide a …

Platelets are versatile cells: New discoveries in hemostasis, thrombosis, immune responses, tumor metastasis and beyond

XR Xu, D Zhang, BE Oswald, N Carrim… - Critical reviews in …, 2016 - Taylor & Francis
Platelets are small anucleate blood cells generated from megakaryocytes in the bone
marrow and cleared in the reticuloendothelial system. At the site of vascular injury, platelet …

[HTML][HTML] Tumor-derived exosomes induce the formation of neutrophil extracellular traps: implications for the establishment of cancer-associated thrombosis

AC Leal, DM Mizurini, T Gomes, NC Rochael… - Scientific reports, 2017 - nature.com
Cancer patients are at an increased risk of developing thromboembolic complications.
Several mechanisms have been proposed to explain cancer-associated thrombosis …

Tumor-derived tissue factor–positive microparticles and venous thrombosis in cancer patients

JE Geddings, N Mackman - Blood, The Journal of the American …, 2013 - ashpublications.org
Patients with cancer have an increased risk for venous thrombosis. Interestingly, different
cancer types have different rates of thrombosis, with pancreatic cancer having one of the …

Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles

SM Davidson, CM Boulanger, E Aikawa… - Cardiovascular …, 2023 - academic.oup.com
Extracellular vesicles (EVs) are nanosized vesicles with a lipid bilayer that are released from
cells of the cardiovascular system, and are considered important mediators of intercellular …

Activation of blood coagulation in cancer: implications for tumour progression

LG Lima, RQ Monteiro - Bioscience reports, 2013 - portlandpress.com
Several studies have suggested a role for blood coagulation proteins in tumour progression.
Herein, we discuss (1) the activation of the blood clotting cascade in the tumour …

The emerging roles of microvesicles in liver diseases

S Lemoinne, D Thabut, C Housset, R Moreau… - Nature reviews …, 2014 - nature.com
Microvesicles (MVs) are extracellular vesicles released by virtually all cells, under both
physiological and pathological conditions. They contain lipids, proteins, RNAs and …

[HTML][HTML] Extracellular vesicles linking inflammation, cancer and thrombotic risks

S Beck, B Hochreiter, JA Schmid - Frontiers in cell and developmental …, 2022 - frontiersin.org
Extracellular vesicles (EVs) being defined as lipid-bilayer encircled particles are released by
almost all known mammalian cell types and represent a heterogenous set of cell fragments …

[HTML][HTML] Characterization of microvesicles released from human red blood cells

DB Nguyen, TB Thuy Ly, MC Wesseling… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Extracellular vesicles (EVs) are spherical fragments of cell membrane
released from various cell types under physiological as well as pathological conditions …

[HTML][HTML] Thrombosis in VEXAS syndrome

TM Oo, JTJ Koay, SF Lee, SMS Lee, XR Lim… - Journal of thrombosis …, 2022 - Springer
VEXAS syndrome, an autoinflammatory syndrome due to a Ubiquitin Like Modifier Activating
Enzyme 1 (UBA1) somatic mutation, has a high thrombotic burden. We report a case of a 69 …