[HTML][HTML] Wnt and PI3K/Akt/mTOR survival pathways as therapeutic targets in glioblastoma
A Barzegar Behrooz, Z Talaie, F Jusheghani… - International journal of …, 2022 - mdpi.com
Glioblastoma (GBM) is a devastating type of brain tumor, and current therapeutic treatments,
including surgery, chemotherapy, and radiation, are palliative at best. The design of effective …
including surgery, chemotherapy, and radiation, are palliative at best. The design of effective …
Frontiers in the treatment of glioblastoma: Past, present and emerging
Glioblastoma (GBM) is one of the most aggressive cancers of the brain. Despite extensive
research over the last several decades, the survival rates for GBM have not improved and …
research over the last several decades, the survival rates for GBM have not improved and …
[HTML][HTML] The research progress of antiangiogenic therapy, immune therapy and tumor microenvironment
H Hu, Y Chen, S Tan, S Wu, Y Huang, S Fu… - Frontiers in …, 2022 - frontiersin.org
Anti-angiogenesis therapy, a promising strategy against cancer progression, is limited by
drug-resistance, which could be attributed to changes within the tumor microenvironment …
drug-resistance, which could be attributed to changes within the tumor microenvironment …
[HTML][HTML] Hypoxia: the cornerstone of glioblastoma
M Domènech, A Hernández, A Plaja… - International journal of …, 2021 - mdpi.com
Glioblastoma is the most aggressive form of brain tumor in adults and is characterized by the
presence of hypervascularization and necrosis, both caused by a hypoxic …
presence of hypervascularization and necrosis, both caused by a hypoxic …
[HTML][HTML] Exosome-based nanoimmunotherapy targeting TAMs, a promising strategy for glioma
H Luo, H Zhang, J Mao, H Cao, Y Tao, G Zhao… - Cell Death & …, 2023 - nature.com
Exosomes, the cell-derived small extracellular vehicles, play a vital role in intracellular
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …
communication by reciprocally transporting DNA, RNA, bioactive protein, chains of glucose …
[HTML][HTML] Tumor-associated microglia and macrophages in the glioblastoma microenvironment and their implications for therapy
RS Andersen, A Anand, DSL Harwood, BW Kristensen - Cancers, 2021 - mdpi.com
Simple Summary Patients with glioblastoma—the most frequent and malignant primary brain
tumor—have a poor prognosis with a median survival of less than 15 months. Despite …
tumor—have a poor prognosis with a median survival of less than 15 months. Despite …
Unraveling the Plasma Protein Corona by Ultrasonic Cavitation Augments Active‐Transporting of Liposome in Solid Tumor
G Wang, Y Jiang, J Xu, J Shen, T Lin, J Chen… - Advanced …, 2023 - Wiley Online Library
Ligand/receptor‐mediated targeted drug delivery has been widely recognized as a
promising strategy for improving the clinical efficacy of nanomedicines but is attenuated by …
promising strategy for improving the clinical efficacy of nanomedicines but is attenuated by …
The landscape of biomimetic nanovesicles in brain diseases
Q You, F Liang, G Wu, F Cao, J Liu, Z He… - Advanced …, 2024 - Wiley Online Library
Brain diseases, such as brain tumors, neurodegenerative diseases, cerebrovascular
diseases, and brain injuries, are caused by various pathophysiological changes, which pose …
diseases, and brain injuries, are caused by various pathophysiological changes, which pose …
[HTML][HTML] New directions in the therapy of glioblastoma
K Szklener, M Mazurek, M Wieteska, M Wacławska… - Cancers, 2022 - mdpi.com
Simple Summary Despite the continuous development of treatment technology,
glioblastoma remains a challenge for modern medicine. The standard of care remains a …
glioblastoma remains a challenge for modern medicine. The standard of care remains a …
[HTML][HTML] Macrophages in recurrent glioblastoma as a prognostic factor in the synergistic system of the tumor microenvironment
N Montemurro, B Pahwa, A Tayal, A Shukla… - Neurology …, 2023 - mdpi.com
Glioblastoma (GBM) is a common and highly malignant primary tumor of the central nervous
system in adults. Ever more recent papers are focusing on understanding the role of the …
system in adults. Ever more recent papers are focusing on understanding the role of the …