[HTML][HTML] Oxidative stress: a suitable therapeutic target for optic nerve diseases?

F Buonfiglio, EW Böhm, N Pfeiffer, A Gericke - Antioxidants, 2023 - mdpi.com
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …

[HTML][HTML] Immunomodulatory and antioxidant drugs in glaucoma treatment

F Buonfiglio, N Pfeiffer, A Gericke - Pharmaceuticals, 2023 - mdpi.com
Glaucoma, a group of diseases characterized by progressive retinal ganglion cell loss,
cupping of the optic disc, and a typical pattern of visual field defects, is a leading cause of …

Amination-mediated nano eye-drops with enhanced corneal permeability and effective burst release for acute glaucoma treatment

DD Nguyen, CH Yao, SJ Lue, CJ Yang, YH Su… - Chemical Engineering …, 2023 - Elsevier
The development of topical formulations with advanced functions to overcome the poor and
sluggish permeability/bioavailability of traditional eye drops into interior of the eye is …

[HTML][HTML] Psychopharmacological treatment, intraocular pressure and the risk of glaucoma: a review of literature

AM Ciobanu, V Dionisie, C Neagu, OM Bolog… - Journal of Clinical …, 2021 - mdpi.com
Through the years, the available psychopharmacological treatments have expanded with
numerous new drugs. Besides weight gain, gastro-intestinal problems or Parkinson-like …

[HTML][HTML] Peroxisome proliferator-activated receptor α activation protects retinal ganglion cells in ischemia-reperfusion retinas

F Yao, X Zhang, X Yao, X Ren, X Xia, J Jiang… - Frontiers in …, 2021 - frontiersin.org
Background and Objective: Retinal ischemia-reperfusion (IR) leads to massive loss of retinal
ganglion cells (RGC) and characterizes several blind-causing ophthalmic diseases …

[HTML][HTML] Nuclear factor erythroid 2-related factor 2 agonist protects retinal ganglion cells in glutamate excitotoxicity retinas

Y An, H Li, M Wang, Z Xia, L Ding, X Xia - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Objective To investigate whether tert-Butylhydroquinone (TBHQ) can ameliorate oxidative
stress and inflammation induced by glutamate excitotoxicity, and mediate retinal ganglion …

Therapeutic effects of tetrahedral framework nucleic acids and tFNAs‐miR22 on retinal ischemia/reperfusion injury

X Xu, Y Fu, D Luo, L Zhang, X Huang, Y Chen… - Cell …, 2024 - Wiley Online Library
Retinal ischemia/reperfusion injury (RI/R) is a common pathological process in ophthalmic
diseases, which can cause severe visual impairment. The mechanisms underlying RI/R …

Pharmaceutical In Situ Gel for Glaucoma: Recent Trends and Development with an Update on Research and Patents

R Deshmukh, R Singh, S Mishra - Critical Reviews™ in …, 2024 - dl.begellhouse.com
Glaucoma is a progressive visual polyneuropathy characterized by retinal ganglion cell
atrophy and optic nerve head changes. It's generally triggered due to increased intraocular …

[HTML][HTML] Silicone oil-induced glaucomatous neurodegeneration in Rhesus Macaques

A Moshiri, F Fang, P Zhuang, H Huang, X Feng… - International Journal of …, 2022 - mdpi.com
Previously, we developed a simple procedure of intracameral injection of silicone oil (SO)
into mouse eyes and established the mouse SOHU (SO-induced ocular hypertension under …

[HTML][HTML] Lens subluxation after use of a percussion massage gun: a case report

J Mu, W Fan - Medicine, 2022 - journals.lww.com
Interventions: The patient underwent phacoemulsification and anterior vitrectomy. After
surgery, the patient was given eye drops containing tobramycin, dexamethasone, 0.1 …