[HTML][HTML] Naturally occurring anti-cancer compounds: shining from Chinese herbal medicine

H Luo, CT Vong, H Chen, Y Gao, P Lyu, L Qiu, M Zhao… - Chinese medicine, 2019 - Springer
Numerous natural products originated from Chinese herbal medicine exhibit anti-cancer
activities, including anti-proliferative, pro-apoptotic, anti-metastatic, anti-angiogenic effects …

Cancer stem cells: A review from origin to therapeutic implications

MR Atashzar, R Baharlou, J Karami… - Journal of cellular …, 2020 - Wiley Online Library
Cancer stem cells (CSCs), also known as tumor‐initiating cells (TICs), are elucidated as
cells that can perpetuate themselves via autorestoration. These cells are highly resistant to …

Absorption, metabolism, anti-cancer effect and molecular targets of epigallocatechin gallate (EGCG): An updated review

RY Gan, HB Li, ZQ Sui, H Corke - Critical reviews in food science …, 2018 - Taylor & Francis
Green tea is one of the most popular beverages in the world, especially in Asian countries.
Consumption of green tea has been demonstrated to possess many health benefits, which …

[HTML][HTML] Molecular targets of epigallocatechin—Gallate (EGCG): A special focus on signal transduction and cancer

A Negri, V Naponelli, F Rizzi, S Bettuzzi - Nutrients, 2018 - mdpi.com
Green tea is a beverage that is widely consumed worldwide and is believed to exert effects
on different diseases, including cancer. The major components of green tea are catechins, a …

Medicinal chemistry strategies to discover P-glycoprotein inhibitors: An update

J Dong, Z Qin, WD Zhang, G Cheng, AG Yehuda… - Drug Resistance …, 2020 - Elsevier
The presence of multidrug resistance (MDR) in malignant tumors is one of the primary
causes of treatment failure in cancer chemotherapy. The overexpression of the ATP binding …

[HTML][HTML] Natural products and synthetic analogs as a source of antitumor drugs

J Sharifi-Rad, A Ozleyen, T Boyunegmez Tumer… - Biomolecules, 2019 - mdpi.com
Cancer is a heterogeneous disease and one of the major issues of health concern,
especially for the public health system globally. Nature is a source of anticancer drugs with …

[HTML][HTML] EGCG adjuvant chemotherapy: Current status and future perspectives

L Wang, P Li, K Feng - European journal of medicinal chemistry, 2023 - Elsevier
The resistance of cancer cells to chemotherapeutic drugs greatly reduces the therapeutic
effect in cancer patients, and the toxic side effects caused by chemotherapy also seriously …

[HTML][HTML] The adaptive transition of glioblastoma stem cells and its implications on treatments

Z Wang, H Zhang, S Xu, Z Liu, Q Cheng - Signal transduction and …, 2021 - nature.com
Glioblastoma is the most malignant tumor occurring in the human central nervous system
with overall median survival time< 14.6 months. Current treatments such as chemotherapy …

[HTML][HTML] Glioblastoma Stem-Like Cells, Metabolic Strategy to Kill a Challenging Target

D Garnier, O Renoult, MC Alves-Guerra, F Paris… - Frontiers in …, 2019 - frontiersin.org
Over the years, substantial evidence has definitively confirmed the existence of cancer stem-
like cells within tumors such as Glioblastoma (GBM). The importance of Glioblastoma stem …

[HTML][HTML] Epigallocatechin-3-gallate targets cancer stem-like cells and enhances 5-fluorouracil chemosensitivity in colorectal cancer

S Toden, HM Tran, OA Tovar-Camargo, Y Okugawa… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Resistance to cytotoxic chemotherapy is a major cause of mortality in colorectal cancer
(CRC) patients. A small subset of cancer cells, termed “cancer stem cells”(CSCs), are …