Recent advances in natural polyphenol research
I Dini, L Grumetto - Molecules, 2022 - mdpi.com
Polyphenols are secondary metabolites produced by plants, which contribute to the plant's
defense against abiotic stress conditions (eg, UV radiation and precipitation), the aggression …
defense against abiotic stress conditions (eg, UV radiation and precipitation), the aggression …
Oxidative stress: a suitable therapeutic target for optic nerve diseases?
F Buonfiglio, EW Böhm, N Pfeiffer, A Gericke - Antioxidants, 2023 - mdpi.com
Optic nerve disorders encompass a wide spectrum of conditions characterized by the loss of
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …
retinal ganglion cells (RGCs) and subsequent degeneration of the optic nerve. The etiology …
The potential effects of quercetin-loaded nanoliposomes on amoxicillin/clavulanate-induced hepatic damage: targeting the Sirt1/Nrf2/Nf-κB signaling pathway and …
Amoxicillin/clavulanate (Co-Amox), a commonly used antibiotic for the treatment of bacterial
infections, has been associated with drug-induced liver damage. Quercetin (QR), a naturally …
infections, has been associated with drug-induced liver damage. Quercetin (QR), a naturally …
Counteracting Immunosenescence—Which Therapeutic Strategies Are Promising?
C Hieber, S Grabbe, M Bros - Biomolecules, 2023 - mdpi.com
Aging attenuates the overall responsiveness of the immune system to eradicate pathogens.
The increased production of pro-inflammatory cytokines by innate immune cells under basal …
The increased production of pro-inflammatory cytokines by innate immune cells under basal …
Sphingolipid levels and signaling via resveratrol and antioxidant actions in cardiometabolic risk and disease
Resveratrol (RSV) is a phenolic compound with strong antioxidant activity, which is
generally associated with the beneficial effects of wine on human health. All resveratrol …
generally associated with the beneficial effects of wine on human health. All resveratrol …
Immunomodulatory and antioxidant drugs in glaucoma treatment
F Buonfiglio, N Pfeiffer, A Gericke - Pharmaceuticals, 2023 - mdpi.com
Glaucoma, a group of diseases characterized by progressive retinal ganglion cell loss,
cupping of the optic disc, and a typical pattern of visual field defects, is a leading cause of …
cupping of the optic disc, and a typical pattern of visual field defects, is a leading cause of …
Early aging and premature vascular aging in chronic kidney disease
Aging is the progressive decline of body functions and a number of chronic conditions can
lead to premature aging characterized by frailty, a diseased vasculature, osteoporosis, and …
lead to premature aging characterized by frailty, a diseased vasculature, osteoporosis, and …
[HTML][HTML] Redox mechanisms in autoimmune thyroid eye disease
F Buonfiglio, KA Ponto, N Pfeiffer, GJ Kahaly… - Autoimmunity …, 2024 - Elsevier
Thyroid eye disease (TED) is an autoimmune condition affecting the orbit and the eye with
its adnexa, often occurring as an extrathyroidal complication of Graves' disease (GD). Orbital …
its adnexa, often occurring as an extrathyroidal complication of Graves' disease (GD). Orbital …
In Silico Identification of Natural Products and World-Approved Drugs Targeting the KEAP1/NRF2 Pathway Endowed with Potential Antioxidant Profile
In this study, we applied a computer-based protocol to identify novel antioxidant agents that
can reduce oxidative stress (OxS), which is one of the main hallmarks of several disorders …
can reduce oxidative stress (OxS), which is one of the main hallmarks of several disorders …
[HTML][HTML] A proteasome-dependent inhibition of SIRT-1 by the resveratrol analogue 4, 4′-dihydroxy-trans-stilbene
V Livraghi, L Mazza, F Chiappori, M Cardano… - Journal of Traditional …, 2024 - Elsevier
Background and aim Resveratrol (RSV), is a stilbene-based compound exerting wide
biological properties. Its analogue 4, 4′-dihydroxy-trans-stilbene (DHS) has shown …
biological properties. Its analogue 4, 4′-dihydroxy-trans-stilbene (DHS) has shown …