Epidemiology of heart failure

A Groenewegen, FH Rutten, A Mosterd… - European journal of …, 2020 - Wiley Online Library
The heart failure syndrome has first been described as an emerging epidemic about 25
years ago. Today, because of a growing and ageing population, the total number of heart …

Epidemiology and aetiology of heart failure

B Ziaeian, GC Fonarow - Nature Reviews Cardiology, 2016 - nature.com
Heart failure (HF) is a rapidly growing public health issue with an estimated prevalence of>
37.7 million individuals globally. HF is a shared chronic phase of cardiac functional …

[PDF][PDF] Pathophysiology of heart failure

E Tanai, S Frantz - Compr Physiol, 2015 - researchgate.net
Heart failure is considered an epidemic disease in the modern world affecting approximately
1% to 2% of adult population. It presents a multifactorial, systemic disease, in which—after …

Efficacy and safety of dapagliflozin in heart failure with mildly reduced or preserved ejection fraction according to age: the DELIVER trial

A Peikert, FA Martinez, M Vaduganathan… - Circulation: Heart …, 2022 - Am Heart Assoc
Background: The prevalence of heart failure with mildly reduced or preserved ejection
fraction markedly increases with age, with older individuals disproportionately facing excess …

Addressing social determinants of health in the care of patients with heart failure: a scientific statement from the American Heart Association

C White-Williams, LP Rossi, VA Bittner, A Driscoll… - Circulation, 2020 - Am Heart Assoc
Heart failure is a clinical syndrome that affects> 6.5 million Americans, with an estimated 550
000 new cases diagnosed each year. The complexity of heart failure management is …

[HTML][HTML] Dysbiosis and compositional alterations with aging in the gut microbiota of patients with heart failure

T Kamo, H Akazawa, W Suda, A Saga-Kamo… - PloS one, 2017 - journals.plos.org
Emerging evidence has suggested a potential impact of gut microbiota on the
pathophysiology of heart failure (HF). However, it is still unknown whether HF is associated …

[HTML][HTML] Senescence and senolytics in cardiovascular disease: Promise and potential pitfalls

WA Owens, A Walaszczyk, I Spyridopoulos… - Mechanisms of Ageing …, 2021 - Elsevier
Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular
disease being the cause of death in 40% of individuals over 65 years old. Ageing is …

[HTML][HTML] Elderly patients' participation in clinical trials

P Shenoy, A Harugeri - Perspectives in clinical research, 2015 - journals.lww.com
The elderly population is a large and the fastest-growing portion of the population
worldwide. The elderly make up the lion's share of patients for certain health conditions …

[HTML][HTML] Management of chronic heart failure in the older population

N Azad, G Lemay - Journal of geriatric cardiology: JGC, 2014 - ncbi.nlm.nih.gov
Chronic heart failure (CHF) is the leading cause of hospitalization for those over the age of
65 and represents a significant clinical and economic burden. About half of hospital re …

Efficacy and safety of LCZ696 (sacubitril-valsartan) according to age: insights from PARADIGM-HF

PS Jhund, M Fu, E Bayram, CH Chen… - European heart …, 2015 - academic.oup.com
Background The age at which heart failure develops varies widely between countries and
drug tolerance and outcomes also vary by age. We have examined the efficacy and safety of …