Experimental models of hepatocellular carcinoma—a preclinical perspective

A Blidisel, I Marcovici, D Coricovac, F Hut… - Cancers, 2021 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC) is characterized by a broad molecular
and genetic heterogeneity, which makes it a challenging subject in terms of the underlying …

[HTML][HTML] Role, molecular mechanism and the potential target of breast cancer stem cells in breast cancer development

T Zhang, H Zhou, K Wang, X Wang, M Wang… - Biomedicine & …, 2022 - Elsevier
Breast cancer (BC) is one of the most common malignant tumors in women globally, and its
occurrence has surpassed lung cancer and become the biggest threat for women. At …

Lysyl oxidase-like 3 restrains mitochondrial ferroptosis to promote liver cancer chemoresistance by stabilizing dihydroorotate dehydrogenase

M Zhan, Y Ding, S Huang, Y Liu, J Xiao, H Yu… - Nature …, 2023 - nature.com
To overcome chemotherapy resistance, novel strategies sensitizing cancer cells to
chemotherapy are required. Here, we screen the lysyl-oxidase (LOX) family to clarify its …

Transarterial embolization modulates the immune response within target and nontarget hepatocellular carcinomas in a rat model

DJ Tischfield, A Gurevich, O Johnson, I Gatmaytan… - Radiology, 2022 - pubs.rsna.org
Background Transarterial embolization (TAE) is the most common treatment for
hepatocellular carcinoma (HCC); however, there remain limited data describing the …

Downregulated ferroptosis-related gene STEAP3 as a novel diagnostic and prognostic target for hepatocellular carcinoma and its roles in immune regulation

Y Yan, Q Liang, Z Xu, J Huang, X Chen… - Frontiers in cell and …, 2021 - frontiersin.org
Ferroptosis, a distinct type of regulated cell death, has been reported to be involved in the
tumorigenesis of liver hepatocellular carcinoma (LIHC). However, the precise functions and …

Locoregional combined with systemic therapies for advanced hepatocellular carcinoma: an inevitable trend of rapid development

X Li, Y Wang, X Ye, P Liang - Frontiers in Molecular Biosciences, 2021 - frontiersin.org
Despite the application of antiviral drugs and improved surveillance tools, the number of
patients diagnosed with hepatocellular carcinoma (HCC) at an advanced stage and with a …

[HTML][HTML] Immunotherapeutic approaches in Hepatocellular carcinoma: Building blocks of hope in near future

N Minaei, R Ramezankhani, A Tamimi, A Piryaei… - European Journal of …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is the most common type of primary hepatic cancer and is
among the major causes of mortality due to cancer. Due to the lack of efficient conventional …

Lamin B1 is a potential therapeutic target and prognostic biomarker for hepatocellular carcinoma

Y Yang, L Gao, J Chen, W Xiao, R Liu, H Kan - Bioengineered, 2022 - Taylor & Francis
Hepatocellular carcinoma (HCC) is an aggressive malignancy. Previous studies have found
that lamin B1 (LMNB1) contributes to the development of human cancers. However, the …

Tumor Treating Fields (TTFields) Concomitant with Sorafenib Inhibit Hepatocellular Carcinoma In Vitro and In Vivo

S Davidi, S Jacobovitch, A Shteingauz… - Cancers, 2022 - mdpi.com
Simple Summary Hepatocellular carcinoma (HCC), an advanced liver cancer, has poor
prognosis and limited treatment options. Tumor Treating Fields (TTFields) therapy is a novel …

Role of immunotherapy in the management of hepatocellular carcinoma: current standards and future directions

A Weinmann, PR Galle - Current Oncology, 2020 - mdpi.com
Role of immunotherapy in the management of hepatocellular carcinoma: current standards and
future directions Page 1 S152 Current Oncology, Vol. 27, Supp. 3, November 2020 © 2020 …