Drug delivery systems for programmed and on-demand release

P Davoodi, LY Lee, Q Xu, V Sunil, Y Sun, S Soh… - Advanced drug delivery …, 2018 - Elsevier
With the advancement in medical science and understanding the importance of
biodistribution and pharmacokinetics of therapeutic agents, modern drug delivery research …

[HTML][HTML] An overview of the production methods for core–shell microspheres for parenteral controlled drug delivery

RS van der Kooij, R Steendam, HW Frijlink… - European Journal of …, 2022 - Elsevier
Core-shell microspheres hold great promise as a drug delivery system because they offer
several benefits over monolithic microspheres in terms of release kinetics, for instance a …

Precise control of PLG microsphere size provides enhanced control of drug release rate

C Berkland, M King, A Cox, KK Kim, DW Pack - Journal of controlled release, 2002 - Elsevier
An important limitation in the development of biodegradable polymer microspheres for
controlled-release drug delivery applications has been the difficulty of specifically designing …

Approaches to improve therapeutic efficacy of biodegradable PLA/PLGA microspheres: a review

SL Bee, ZAA Hamid, M Mariatti, BH Yahaya… - Polymer …, 2018 - Taylor & Francis
This review aims to provide a comprehensive overview about various innovative strategies
that have been employed by recent researchers to overcome with the shortcomings …

Bone regeneration from PLGA micro‐nanoparticles

I Ortega-Oller, M Padial-Molina… - BioMed research …, 2015 - Wiley Online Library
Poly‐lactic‐co‐glycolic acid (PLGA) is one of the most widely used synthetic polymers for
development of delivery systems for drugs and therapeutic biomolecules and as component …

Sequential release of vascular endothelial growth factor-A and bone morphogenetic protein-2 from osteogenic scaffolds assembled by PLGA microcapsules: A …

Y Wang, L Zhao, L Zhou, C Chen, G Chen - International Journal of …, 2023 - Elsevier
Bone regeneration is a complex process sequentially regulated by multiple cytokines at
different stages. Vascular endothelial growth factor-A (VEGF-A) and bone morphogenetic …

Core–shell particles for controllable release of drug

D He, S Wang, L Lei, Z Hou, P Shang, X He… - Chemical Engineering …, 2015 - Elsevier
In this review paper, the state-of-the-art knowledge on core–shell particles for controllable
release of drug (s) is presented. Two categories of core–shell particles, including core–shell …

[HTML][HTML] Bone morphogenetic protein-2 loaded poly (D, L-lactide-co-glycolide) microspheres enhance osteogenic potential of gelatin/hydroxyapatite/β-tricalcium …

HC Chang, C Yang, F Feng, FH Lin, CH Wang… - Journal of the Formosan …, 2017 - Elsevier
Background/Purpose Sufficient bony support is essential to ensure the success of dental
implant osseointegration. However, the reconstruction of vertical ridge deficiencies is still a …

Uniform biodegradable microparticle systems for controlled release

Y Xia, DW Pack - Chemical Engineering Science, 2015 - Elsevier
Drug delivery methods can impact efficacy as much as the nature of the drug itself.
Microparticles made of biodegradable polymers such as poly (D, l-lactide-co-glycolide) and …

Controlled protein release from monodisperse biodegradable double-wall microspheres of controllable shell thickness

Y Xia, PF Ribeiro, DW Pack - Journal of controlled release, 2013 - Elsevier
Biodegradable polymer microparticles are promising delivery depots for protein therapeutics
due to their relatively simple fabrication and facile administration. Double-wall microspheres …