Antifungal resistance: current trends and future strategies to combat

NP Wiederhold - Infection and drug resistance, 2017 - Taylor & Francis
Antifungal resistance represents a major clinical challenge to clinicians responsible for
treating invasive fungal infections due to the limited arsenal of systemically available …

[HTML][HTML] An Update on the Roles of Non-albicans Candida Species in Vulvovaginitis

O Makanjuola, F Bongomin, SA Fayemiwo - Journal of Fungi, 2018 - mdpi.com
Candida species are one of the commonest causes of vaginitis in healthy women of
reproductive age. Vulvovaginal candidiasis (VVC) is characterized by vulvovaginal itching …

Changing epidemiology of candidaemia in Australia

B Chapman, M Slavin, D Marriott… - Journal of …, 2017 - academic.oup.com
Objectives Knowledge of contemporary epidemiology of candidaemia is essential. We
aimed to identify changes since 2004 in incidence, species epidemiology and antifungal …

The antifungal arsenal: alternative drugs and future targets

NP Wiederhold - International journal of antimicrobial agents, 2018 - Elsevier
Clinically available antifungals for the treatment of invasive fungal infections primarily target
either ergosterol in the fungal cell membrane or 1, 3-β-D-glucan in the fungal cell wall …

Distribution and antifungal susceptibility pattern of Candida species from mainland China: A systematic analysis

H Bilal, M Shafiq, B Hou, R Islam, MN Khan, RU Khan… - Virulence, 2022 - Taylor & Francis
Antifungal resistance to Candida pathogens increases morbidity and mortality of
immunosuppressive patients, an emerging crisis worldwide. Understanding the Candida …

Decreased echinocandin susceptibility in Candida parapsilosis causing candidemia and emergence of a pan-echinocandin resistant case in China

Y Ning, M Xiao, DS Perlin, Y Zhao, M Lu… - Emerging Microbes & …, 2023 - Taylor & Francis
Candida parapsilosis is becoming a predominant non-albicans cause of invasive
candidiasis (IC). Echinocandins are the preferred choice for IC treatment and prophylaxis …

Antifungal susceptibility of invasive Candida bloodstream isolates from the Asia-Pacific region

TY Tan, LY Hsu, MM Alejandria, R Chaiwarith… - …, 2016 - academic.oup.com
Bloodstream infections caused by Candida species are of increasing importance and
associated with significant mortality. We performed a multi-centre prospective observational …

Five-year national surveillance of invasive candidiasis: species distribution and azole susceptibility from the China Hospital Invasive Fungal Surveillance Net (CHIF …

M Xiao, ZY Sun, M Kang, DW Guo, K Liao… - Journal of Clinical …, 2018 - Am Soc Microbiol
Data on the epidemiology of invasive candidiasis (IC) and the antifungal susceptibility of
Candida isolates in China are still limited. Here we report on surveillance for IC from the …

Epidemiology of Candidemia and Antifungal Susceptibility in Invasive Candida Species in the Asia-Pacific Region

H Wang, YC Xu, PR Hsueh - Future microbiology, 2016 - Taylor & Francis
In the Asia-Pacific region, Candida albicans is the predominant Candida species causing
invasive candidiasis/candidemia in Australia, Japan, Korea, Hong Kong, Malaysia …

[HTML][HTML] The yin and yang of current antifungal therapeutic strategies: how can we harness our natural defenses?

T Di Mambro, I Guerriero, L Aurisicchio… - Frontiers in …, 2019 - frontiersin.org
Fungal infections have aroused much interest over the last years because of their
involvement in several human diseases. Immunocompromission due to transplant-related …