Antimicrobial peptides, conventional antibiotics, and their synergistic utility for the treatment of drug‐resistant infections
Y Zhu, W Hao, X Wang, J Ouyang… - Medicinal Research …, 2022 - Wiley Online Library
Antimicrobial peptides (AMPs), also known as host defense peptides (HDPs), are important
effector immune defense molecules in multicellular organisms. AMPs exert their …
effector immune defense molecules in multicellular organisms. AMPs exert their …
The role of reactive species on innate immunity
CMC Andrés, JM Pérez de la Lastra, CA Juan, FJ Plou… - Vaccines, 2022 - mdpi.com
This review examines the role of reactive species RS (of oxygen ROS, nitrogen RNS and
halogen RHS) on innate immunity. The importance of these species in innate immunity was …
halogen RHS) on innate immunity. The importance of these species in innate immunity was …
Secondary amine pendant β-peptide polymers displaying potent antibacterial activity and promising therapeutic potential in treating MRSA-induced wound infections …
Y Qian, S Deng, Z Cong, H Zhang, Z Lu… - Journal of the …, 2022 - ACS Publications
Interest in developing antibacterial polymers as synthetic mimics of host defense peptides
(HPDs) has accelerated in recent years to combat antibiotic-resistant bacterial infections …
(HPDs) has accelerated in recent years to combat antibiotic-resistant bacterial infections …
Antimicrobial mechanisms and clinical application prospects of antimicrobial peptides
X Li, S Zuo, B Wang, K Zhang, Y Wang - Molecules, 2022 - mdpi.com
Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …
are components of the innate immunity of almost all living things. They play an important role …
Light-activated molecular machines are fast-acting broad-spectrum antibacterials that target the membrane
The increasing occurrence of antibiotic-resistant bacteria and the dwindling antibiotic
research and development pipeline have created a pressing global health crisis. Here, we …
research and development pipeline have created a pressing global health crisis. Here, we …
Structure–activity relationships of antibacterial peptides
Antimicrobial peptides play a crucial role in innate immunity, whose components are mainly
peptide‐based molecules with antibacterial properties. Indeed, the exploration of the …
peptide‐based molecules with antibacterial properties. Indeed, the exploration of the …
Novel approaches to combat medical device-associated biofilms
X Li, L Sun, P Zhang, Y Wang - Coatings, 2021 - mdpi.com
Biofilms are aggregates formed as a protective survival state by microorganisms to adapt to
the environment and can be resistant to antimicrobial agents and host immune responses …
the environment and can be resistant to antimicrobial agents and host immune responses …
[HTML][HTML] An update on antimicrobial peptides (AMPs) and their delivery strategies for wound infections
Bacterial infections occur when wound healing fails to reach the final stage of healing, which
is usually hindered by the presence of different pathogens. Different topical antimicrobial …
is usually hindered by the presence of different pathogens. Different topical antimicrobial …
Synthesis and molecular docking study of α-aminophosphonates as potential multi-targeting antibacterial agents
Antibacterial compounds that reduce extracellular polymeric substances (EPS) are needed
to avoid bacterial biofilms in water pipelines. Herein, green one-pot synthesis of α …
to avoid bacterial biofilms in water pipelines. Herein, green one-pot synthesis of α …
A Novel Antimicrobial Peptide Spampcin56–86 from Scylla paramamosain Exerting Rapid Bactericidal and Anti-Biofilm Activity In Vitro and Anti-Infection In Vivo
M Jiang, R Chen, J Zhang, F Chen… - International Journal of …, 2022 - mdpi.com
The abuse of antibiotics leads to the increase of bacterial resistance, which seriously
threatens human health. Therefore, there is an urgent need to find effective alternatives to …
threatens human health. Therefore, there is an urgent need to find effective alternatives to …