Healthy functioning of the human brain relies on effective shielding of the sensitive neural
microenvironment from potentially disruptive xenobiotic agents circulating in the periphery …

Serotonin (5-HT) receptors are part of the G protein-coupled and ligand-gated ion channel
families. 5-HT exerts its diverse actions by binding to cell surface receptors which can be …

Facile arylation and alkylation of nitropyridine N-oxides were developed through the
reactions of Grignard reagents with nitropyridine N-oxides. For the same 4-nitropyridine N …

The critical role of serotonin (5-hydroxytryptamine; 5-HT) and its receptors (5-HTRs) in the
pathophysiology of diverse neuropsychiatric and neurodegenerative disorders render them …

Herein a simple, metal-free synthesis of 2-alkyl-, 2-cycloalkyl-, 2-aryl-, and 2-heteroaryl-
substituted pyridine 3, 4-dicarboxylates and their N-oxides from the corresponding methyl …

A new neodymium [Nd (BCPN) 3 (NO 3) 3 (H 2 O) 2] complex with 3-bromo-2-chloro-6-
picolinic N-oxide was synthesized and characterized by means of spectroscopic studies and …

Abstract Introduction:[18F] MeFWAY has been developed for imaging the serotonin 1A
receptors in the brain. The purpose of this study were to verify the metabolic stability of [18F] …

The unprecedented substitution of a nitro group with aryl or alkenyl groups of Grignard
reagents affords 2-aryl or alkenylpyridine N-oxides in modest to high yields with high …

X-ray crystal structures of two isomers C8H11N3O3, ie 2-N-ethylamino-5-methyl-4-
nitropyridine N-oxide (EN5MPO) and 2-N-ethylamino-3-methyl-4-nitropyridine N-oxide …

The aim of this study was to develop a highly reliable radiofluorination method for the
preparation of N‐{2‐[4‐(2‐methoxyphenyl) piperazinyl] ethyl}‐N‐(2‐pyridyl)‐N‐(4‐18F …