Pancreatic endocrine cells are produced from a dynamic epithelium in a process that, as in
any developing organ, is driven by interacting programs of spatiotemporally regulated …

Multiple endocrine neoplasia type 1 (MEN1) is a rare autosomal dominant syndrome caused
by inactivating pathogenic variants in the tumor suppressor gene menin 1 on chromosome …

Pancreatic islets are innervated by autonomic and sensory nerves that influence their
function. Analyzing the innervation process should provide insight into the nerve-endocrine …

During embryonic development, pancreatic epithelial cells engage in concomitant
morphogenetic and fate specification events that will give rise to the final organ architecture …

The enteric nervous system (ENS) arises from the coordinated migration, expansion and
differentiation of vagal and sacral neural crest progenitor cells. During development, vagal …

Proper functioning of the digestive system is ensured by coordinated action of the central
and peripheral nervous systems (PNS). Peripheral innervation of the digestive system can …

The pancreas of adult mammals displays a branched structure which transports digestive
enzymes produced in the distal acini through a tree-like network of ducts into the duodenum …

The mammalian pancreas is densely innervated by both the sympathetic and
parasympathetic nervous systems, which control exocrine and endocrine secretion. During …

Over the past few years, extensive efforts have been made to generate in-vitro pancreatic
micro-tissue, for disease modeling or cell replacement approaches in pancreatic related …

Background The sympathetic nervous system plays an important role in the regulation of
pancreatic exocrine and endocrine secretion. The results of experimental studies also …