Hydroethidine-and MitoSOX-derived red fluorescence is not a reliable indicator of intracellular superoxide formation: another inconvenient truth
J Zielonka, B Kalyanaraman - Free Radical Biology and Medicine, 2010 - Elsevier
Hydroethidine (HE; or dihydroethidium) is the most popular fluorogenic probe used for
detecting intracellular superoxide radical anion. The reaction between superoxide and HE …
detecting intracellular superoxide radical anion. The reaction between superoxide and HE …
Reactive oxygen species in vascular biology: implications in hypertension
RM Touyz, EL Schiffrin - Histochemistry and cell biology, 2004 - Springer
Reactive oxygen species (ROS), including superoxide (· O 2−), hydrogen peroxide (H 2 O 2),
and hydroxyl anion (OH-), and reactive nitrogen species, such as nitric oxide (NO) and …
and hydroxyl anion (OH-), and reactive nitrogen species, such as nitric oxide (NO) and …
From bedside to bench to bedside: role of renin-angiotensin-aldosterone system in remodeling of resistance arteries in hypertension
EL Schiffrin, RM Touyz - American Journal of Physiology …, 2004 - journals.physiology.org
RESISTANCE ARTERIES are vessels of 100–300 m in lumen diameter that are an important
site of resistance to blood flow. Small artery-dependent increased peripheral resistance may …
site of resistance to blood flow. Small artery-dependent increased peripheral resistance may …
Does vitamin C enhance nitric oxide bioavailability in a tetrahydrobiopterin-dependent manner? In vitro, in vivo and clinical studies
A Mortensen, J Lykkesfeldt - Nitric Oxide, 2014 - Elsevier
Ascorbate (Asc) has been shown to increase nitric oxide (NO) bioavailability and thereby
improve endothelial function in patients showing signs of endothelial dysfunction …
improve endothelial function in patients showing signs of endothelial dysfunction …
Insulin-induced generation of reactive oxygen species and uncoupling of nitric oxide synthase underlie the cerebrovascular insulin resistance in obese rats
PVG Katakam, JA Snipes, MM Steed… - Journal of Cerebral …, 2012 - journals.sagepub.com
Hyperinsulinemia accompanying insulin resistance (IR) is an independent risk factor for
stroke. The objective is to examine the cerebrovascular actions of insulin in Zucker obese …
stroke. The objective is to examine the cerebrovascular actions of insulin in Zucker obese …
Review on the bioactive peptides from marine sources: Indication for health effects
R Ghanbari - International Journal of Peptide Research and …, 2019 - Springer
Food protein-generated bioactive peptides are natural products that have nutraceutical and
pharmaceutical properties. They have been reported various biological roles such as anti …
pharmaceutical properties. They have been reported various biological roles such as anti …
Association of estrogen-related polymorphisms with age at menarche, age at final menstrual period, and stages of the menopausal transition
ES Mitchell, FM Farin, PL Stapleton, JM Tsai, EY Tao… - Menopause, 2008 - journals.lww.com
Objective: To explore the association of estrogen-related polymorphisms with age at
menarche, age at onset and duration of stages of the menopausal transition, and age at final …
menarche, age at onset and duration of stages of the menopausal transition, and age at final …
DAF-FM (4-amino-5-methylamino-2′, 7′-difluorofluorescein) diacetate detects impairment of agonist-stimulated nitric oxide synthesis by elevated glucose in human …
JZ Sheng, D Wang, AP Braun - Journal of Pharmacology and Experimental …, 2005 - ASPET
Elevated plasma glucose, as commonly seen in types I and II diabetes mellitus, is known to
result in endothelial dysfunction, a condition characterized by a loss of nitric oxide (NO) …
result in endothelial dysfunction, a condition characterized by a loss of nitric oxide (NO) …
Increasing dihydrobiopterin causes dysfunction of endothelial nitric oxide synthase in rats in vivo
K Noguchi, N Hamadate, T Matsuzaki… - American Journal …, 2011 - journals.physiology.org
An elevation of oxidized forms of tetrahydrobiopterin (BH4), especially dihydrobiopterin
(BH2), has been reported in the setting of oxidative stress, such as arteriosclerotic …
(BH2), has been reported in the setting of oxidative stress, such as arteriosclerotic …
Endothelium-specific sepiapterin reductase deficiency in DOCA-salt hypertension
JY Youn, T Wang, J Blair, KM Laude… - American Journal …, 2012 - journals.physiology.org
The endothelial nitric oxide synthase (eNOS) requires tetrahydrobiopterin (H4B) as a
cofactor and, in its absence, produces superoxide (O2·−) rather than nitric oxide (NO·), a …
cofactor and, in its absence, produces superoxide (O2·−) rather than nitric oxide (NO·), a …