Effects of lactate, super-GDF9, and low oxygen tension during bi-phasic in vitro maturation on the bioenergetic profiles of mouse cumulus–oocyte complex

N Akin, G Ates, L von Mengden, AC Herta… - Biology of …, 2023 - academic.oup.com
In vitro maturation (IVM) is an alternative assisted reproductive technology with reduced
hormone-related side effects and treatment burden compared to conventional IVF …

Mitochondrial Dysfunction in Advanced Maternal Aged Cumulus Cells: A Possible Link to ATP Synthase Impairment?

S Almeida-Reis, A Carvalho, C Dias, R Brito, R Silva… - Biomolecules, 2024 - mdpi.com
Age-related changes in the mitochondrial status of human cumulus cells (hCCs) impact
oocyte quality; however, the relationship between hCC mitochondrial (dys) function and …

[HTML][HTML] The oocyte microenvironment is altered in adolescents compared to oocyte donors

D Gokyer, S Akinboro, LT Zhou, A Kleinhans… - bioRxiv, 2024 - ncbi.nlm.nih.gov
Study design, size, duration: This was a prospective cohort study. Adolescents (10-19 52
years old, N= 23) and oocyte donors (22-30 years old, N= 31) undergoing ovarian 53 …