Bioorthogonal chemistry for prodrug activation in vivo
Prodrugs have emerged as a major strategy for addressing clinical challenges by improving
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …
drug pharmacokinetics, reducing toxicity, and enhancing treatment efficacy. The emergence …
Understanding cervical cancer at single-cell resolution
Cervical cancer is now the fourth most prevalent malignancy in women worldwide,
representing a tremendous burden of cancer. The heterogeneity of complex tumor …
representing a tremendous burden of cancer. The heterogeneity of complex tumor …
[HTML][HTML] Pan-cancer spatially resolved single-cell analysis reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironment
C Ma, C Yang, A Peng, T Sun, X Ji, J Mi, L Wei… - Molecular Cancer, 2023 - Springer
Cancer-associated fibroblasts (CAFs) are a heterogeneous cell population that plays a
crucial role in remodeling the tumor microenvironment (TME). Here, through the integrated …
crucial role in remodeling the tumor microenvironment (TME). Here, through the integrated …
Tailoring Crystallization Dynamics of CsPbI3 for Scalable Production of Efficient Inorganic Perovskite Solar Cells
All‐inorganic perovskite cesium lead triiodide (CsPbI3) with inorganic nature, low‐
temperature synthesis, and a suitable bandgap is desirable for high‐performance …
temperature synthesis, and a suitable bandgap is desirable for high‐performance …
Off‐Centering of Ge Atoms in GeBi2Te4 and Impact on Thermoelectric Performance
The crystal structure and transport properties of GeBi2Te4 are investigated as a layered
compound with potential applications as thermoelectric materials. A disordered arrangement …
compound with potential applications as thermoelectric materials. A disordered arrangement …
Atom Probe Tomography Advances Chalcogenide Phase‐Change and Thermoelectric Materials
Main‐group chalcogenides show outstanding performance for phase‐change data storage
and thermoelectric energy conversion applications. A common denominator for these …
and thermoelectric energy conversion applications. A common denominator for these …
Optical metasurfaces for tunable vortex beams
VC Su, SY Huang, MH Chen… - Advanced Optical …, 2023 - Wiley Online Library
The pursuit of device miniaturization and the generation of complex output responses has
driven the development of optically tunable metasurfaces. Among these advancements …
driven the development of optically tunable metasurfaces. Among these advancements …
[HTML][HTML] Single cell deciphering of progression trajectories of the tumor ecosystem in head and neck cancer
ZL Liu, XY Meng, RJ Bao, MY Shen, JJ Sun… - Nature …, 2024 - nature.com
Head and neck squamous cell carcinoma is the sixth most common cancer worldwide and
has high heterogeneity and unsatisfactory outcomes. To better characterize the tumor …
has high heterogeneity and unsatisfactory outcomes. To better characterize the tumor …
[HTML][HTML] Deciphering tumor-infiltrating dendritic cells in the single-cell era
Q Huang, F Wang, D Hao, X Li, X Li, T Lei… - … Hematology & Oncology, 2023 - Springer
Dendritic cells (DCs) serve as a pivotal link connecting innate and adaptive immunity by
processing tumor-derived antigens and activating T cells. The advent of single-cell …
processing tumor-derived antigens and activating T cells. The advent of single-cell …
[HTML][HTML] S100P as a potential biomarker for immunosuppressive microenvironment in pancreatic cancer: a bioinformatics analysis and in vitro study
W Hao, Y Zhang, J Dou, P Cui, J Zhu - BMC cancer, 2023 - Springer
Background Immunosuppression is a significant factor contributing to the poor prognosis of
cancer. S100P, a member of the S100 protein family, has been implicated in various …
cancer. S100P, a member of the S100 protein family, has been implicated in various …