[HTML][HTML] Melanocortin-4 receptor regulation of pain

ZX Li, BW Liu, ZG He, HB Xiang - … Acta (BBA)-Molecular Basis of Disease, 2017 - Elsevier
An increasingly high occurrence of chronic pain in patients highlights the importance of
fundamental research. The melanocortin-4 receptor (MC4R) regulation of pain has attracted …

The role of the anterior pretectal nucleus in pain modulation: A comprehensive review

K Genaro, WA Prado - European Journal of Neuroscience, 2021 - Wiley Online Library
Descending pain modulation involves multiple encephalic sites and pathways that range
from the cerebral cortex to the spinal cord. Behavioral studies conducted in the 1980s …

Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock‐in allele

N Parmhans, AD Fuller, E Nguyen… - Journal of …, 2021 - Wiley Online Library
Members of the POU4F/Brn3 transcription factor family have an established role in the
development of retinal ganglion cell (RGCs) types, the main transducers of visual …

Activation of cannabinoid receptor 1 in GABAergic neurons in the rostral anterior insular cortex contributes to the analgesia following common peroneal nerve ligation

M Zhang, C Li, Q Xue, CB Lu, H Zhao, FC Meng… - Neuroscience …, 2023 - Springer
The rostral agranular insular cortex (RAIC) has been associated with pain modulation.
Although the endogenous cannabinoid system (eCB) has been shown to regulate chronic …

Decreased resting-state functional connectivity of periaqueductal gray in temporal lobe epilepsy comorbid with migraine

L Wang, XT Cai, MD Zu, J Zhang, ZR Deng… - Frontiers in …, 2021 - frontiersin.org
Objective: Patients with temporal lobe epilepsy (TLE) are at high risk for having a comorbid
condition of migraine, and these two common diseases are proposed to have some shared …

[HTML][HTML] The antinociceptive effect of anterior pretectal nucleus stimulation is mediated by distinct neurotransmitter mechanisms in descending pain pathways

K Genaro, D Fabris, WA Prado - Brain Research Bulletin, 2019 - Elsevier
Electrical stimulation of the anterior pretectal nucleus (APtN) activates two descending pain
inhibitory pathways. One of these pathways relays in the ipsilateral lateral …

Contribution des canaux calciques de type T supra-spinaux à la douleur neuropathique: rôle du canal Cav3. 2 exprimé dans le noyau prétectal antérieur

S Fayad - 2019 - theses.fr
Résumé Les traitements actuels des neuropathies étant insuffisants, il est nécessaire
d'identifier de nouvelles cibles thérapeutiques. L'isoforme Cav3. 2 des canaux calciques de …