Epigenetic mechanisms in schizophrenia and other psychotic disorders: a systematic review of empirical human findings

L Smigielski, V Jagannath, W Rössler, S Walitza… - Molecular …, 2020 - nature.com
Schizophrenia and other psychotic disorders are highly debilitating psychiatric conditions
that lack a clear etiology and exhibit polygenic inheritance underlain by pleiotropic genes …

Circulating exosomal miRNA as diagnostic biomarkers of neurodegenerative diseases

L Wang, L Zhang - Frontiers in molecular neuroscience, 2020 - frontiersin.org
Neurodegenerative diseases (NDDs) are a group of diseases caused by chronic and
progressive degeneration of neural tissue. The main pathological manifestations are …

MicroRNA schizophrenia: etiology, biomarkers and therapeutic targets

HC Zhang, Y Du, L Chen, ZQ Yuan, Y Cheng - … & Biobehavioral Reviews, 2023 - Elsevier
The three sets of symptoms associated with schizophrenia—positive, negative, and
cognitive—are burdensome and have serious effects on public health, which affects up to …

[HTML][HTML] Biomarkers in schizophrenia: a focus on blood based diagnostics and theranostics

CY Lai, E Scarr, M Udawela, I Everall… - World journal of …, 2016 - ncbi.nlm.nih.gov
Identifying biomarkers that can be used as diagnostics or predictors of treatment response
(theranostics) in people with schizophrenia (Sz) will be an important step towards being able …

Circulating miRNAs as diagnostic biomarkers for Parkinson's disease

AE Roser, L Caldi Gomes, J Schünemann… - Frontiers in …, 2018 - frontiersin.org
Parkinson's disease (PD) is the second most common neurodegenerative disorder
worldwide. Its main neuropathological hallmarks are the degeneration of dopaminergic …

Alterations of microRNA-124 expression in peripheral blood mononuclear cells in pre-and post-treatment patients with major depressive disorder

S He, X Liu, K Jiang, D Peng, W Hong, Y Fang… - Journal of psychiatric …, 2016 - Elsevier
Recently, increasing evidence has indicated that dysfunction of microRNA-124 (miR-124)
might be involved in the pathophysiology and treatment of major depressive disorder (MDD) …

Non-coding RNA as novel players in the pathophysiology of schizophrenia

A Gibbons, M Udawela, B Dean - Non-coding RNA, 2018 - mdpi.com
Schizophrenia is associated with diverse changes in the brain's transcriptome and
proteome. Underlying these changes is the complex dysregulation of gene expression and …

Diagnostic and therapeutic potential of microRNAs in neuropsychiatric disorders: past, present, and future

B Alural, S Genc, SJ Haggarty - Progress in Neuro-Psychopharmacology …, 2017 - Elsevier
Neuropsychiatric disorders are common health problems affecting approximately 1% of the
population. Twin, adoption, and family studies have displayed a strong genetic component …

Diagnostic value of blood-derived microRNAs for schizophrenia: results of a meta-analysis and validation

S Liu, F Zhang, X Wang, YY Shugart, Y Zhao, X Li… - Scientific reports, 2017 - nature.com
There is an increasing interest in searching biomarkers for schizophrenia (SZ) diagnosis,
which overcomes the drawbacks inherent with the subjective diagnostic methods. MicroRNA …

Neuronal development-related miRNAs as biomarkers for Alzheimer's disease, depression, schizophrenia and ionizing radiation exposure

RC Segaran, LY Chan, H Wang… - Current medicinal …, 2021 - ingentaconnect.com
Radiation exposure may induce Alzheimer's disease (AD), depression or schizophrenia. A
number of experimental and clinical studies suggest the involvement of miRNA in the …