Measurement and clinical significance of biomarkers of oxidative stress in humans

I Marrocco, F Altieri, I Peluso - Oxidative medicine and cellular …, 2017 - Wiley Online Library
Oxidative stress is the result of the imbalance between reactive oxygen species (ROS)
formation and enzymatic and nonenzymatic antioxidants. Biomarkers of oxidative stress are …

Oxidative stress in hemodialysis patients: a review of the literature

V Liakopoulos, S Roumeliotis, X Gorny… - Oxidative medicine …, 2017 - Wiley Online Library
Hemodialysis (HD) patients are at high risk for all‐cause mortality and cardiovascular
events. In addition to traditional risk factors, excessive oxidative stress (OS) and chronic …

Effects of uric acid on diabetes mellitus and its chronic complications

Q Xiong, J Liu, Y Xu - International journal of endocrinology, 2019 - Wiley Online Library
With the deepening of the researches on uric acid, especially in the study of metabolic
diseases, uric acid has been found to be closely related to obesity, metabolic syndrome …

Prevalence of hyperuricemia among Chinese adults: a national cross-sectional survey using multistage, stratified sampling

H Liu, XM Zhang, YL Wang, BC Liu - Journal of nephrology, 2014 - Springer
Background Hyperuricemia is a non-communicable disease that threatens human health,
and its prevalence has been increasing in recent decades. However, there have been no …

The role of tissue renin-angiotensin-aldosterone system in the development of endothelial dysfunction and arterial stiffness

AR Aroor, VG DeMarco, G Jia, Z Sun… - Frontiers in …, 2013 - frontiersin.org
Epidemiological studies support the notion that arterial stiffness is an independent predictor
of adverse cardiovascular events contributing significantly to systolic hypertension, impaired …

Urate lowering therapy to improve renal outcomes in patients with chronic kidney disease: systematic review and meta-analysis

T Kanji, M Gandhi, CM Clase, R Yang - BMC nephrology, 2015 - Springer
Background Hyperuricemia may contribute to renal injury. We do not know whether use of
treatments that lower urate reduce the progression of chronic kidney disease (CKD) and …

Uraemic syndrome of chronic kidney disease: altered remote sensing and signalling

SK Nigam, KT Bush - Nature Reviews Nephrology, 2019 - nature.com
Uraemic syndrome (also known as uremic syndrome) in patients with advanced chronic
kidney disease involves the accumulation in plasma of small-molecule uraemic solutes and …

The kidney and uremic toxin removal: glomerulus or tubule?

R Masereeuw, HAM Mutsaers, T Toyohara, T Abe… - Seminars in …, 2014 - Elsevier
Chronic kidney disease (CKD) is a condition that affects approximately 10% of the adult
population in developed countries. In patients with CKD adequate renal clearance is …

Uric acid as a biomarker and a therapeutic target in diabetes

Y Lytvyn, BA Perkins, DZI Cherney - Canadian journal of diabetes, 2015 - Elsevier
Diabetic nephropathy is a long-standing microvascular complication of diabetes mellitus and
is the leading cause of end stage renal disease in developed countries. Current therapeutic …

The altered gut microbiota of high-purine-induced hyperuricemia rats and its correlation with hyperuricemia

X Liu, Q Lv, H Ren, L Gao, P Zhao, X Yang, G Yang… - PeerJ, 2020 - peerj.com
Some studies on the hyperuricemia (HUA) have focused on intestinal bacteria. To better
understand the correlation between gut microbiota and HUA, we established a HUA rat …