[HTML][HTML] Pharmaceutical amorphous solid dispersion: A review of manufacturing strategies

SV Bhujbal, B Mitra, U Jain, Y Gong, A Agrawal… - … Pharmaceutica Sinica B, 2021 - Elsevier
Amorphous solid dispersions (ASDs) are popular for enhancing the solubility and
bioavailability of poorly water-soluble drugs. Various approaches have been employed to …

Connected healthcare: Improving patient care using digital health technologies

A Awad, SJ Trenfield, TD Pollard, JJ Ong… - Advanced Drug Delivery …, 2021 - Elsevier
Now more than ever, traditional healthcare models are being overhauled with digital
technologies of Healthcare 4.0 increasingly adopted. Worldwide, digital devices are …

3D printing as a promising tool in personalized medicine

VM Vaz, L Kumar - Aaps Pharmscitech, 2021 - Springer
Personalized medicine has the potential to revolutionize the healthcare sector, its goal being
to tailor medication to a particular individual by taking into consideration the physiology …

3D printing of a multi-layered polypill containing six drugs using a novel stereolithographic method

P Robles-Martinez, X Xu, SJ Trenfield, A Awad… - Pharmaceutics, 2019 - mdpi.com
Three-dimensional printing (3DP) has demonstrated great potential for multi-material
fabrication because of its capability for printing bespoke and spatially separated material …

[HTML][HTML] Successful oral delivery of poorly water-soluble drugs both depends on the intraluminal behavior of drugs and of appropriate advanced drug delivery systems

BJ Boyd, CAS Bergström, Z Vinarov, M Kuentz… - European Journal of …, 2019 - Elsevier
Poorly water-soluble drugs continue to be a problematic, yet important class of
pharmaceutical compounds for treatment of a wide range of diseases. Their prevalence in …

Shaping the future: recent advances of 3D printing in drug delivery and healthcare

SJ Trenfield, A Awad, CM Madla… - Expert opinion on …, 2019 - Taylor & Francis
ABSTRACT Introduction: Three-dimensional (3D) printing is a relatively new, rapid
manufacturing technology that has found promising applications in the drug delivery and …

M3DISEEN: A novel machine learning approach for predicting the 3D printability of medicines

M Elbadawi, BM Castro, FKH Gavins, JJ Ong… - International Journal of …, 2020 - Elsevier
Artificial intelligence (AI) has the potential to reshape pharmaceutical formulation
development through its ability to analyze and continuously monitor large datasets. Fused …

Automated therapy preparation of isoleucine formulations using 3D printing for the treatment of MSUD: First single-centre, prospective, crossover study in patients

A Goyanes, CM Madla, A Umerji, GD Piñeiro… - International Journal of …, 2019 - Elsevier
Maple syrup urine disease (MSUD) is a rare metabolic disorder with a worldwide prevalence
of 1 in every 185,000 live births. However, certain populations display a significant …

Harnessing artificial intelligence for the next generation of 3D printed medicines

M Elbadawi, LE McCoubrey, FKH Gavins… - Advanced Drug Delivery …, 2021 - Elsevier
Artificial intelligence (AI) is redefining how we exist in the world. In almost every sector of
society, AI is performing tasks with super-human speed and intellect; from the prediction of …

Fused Deposition Modeling (FDM), the new asset for the production of tailored medicines

S Cailleaux, NM Sanchez-Ballester, YA Gueche… - Journal of controlled …, 2021 - Elsevier
Over the last few years, conventional medicine has been increasingly moving towards
precision medicine. Today, the production of oral pharmaceutical forms tailored to patients is …