The role of natural products in drug discovery and development against neglected tropical diseases

PM Cheuka, G Mayoka, P Mutai, K Chibale - Molecules, 2016 - mdpi.com
Endemic in 149 tropical and subtropical countries, neglected tropical diseases (NTDs) affect
more than 1 billion people annually, including 875 million children in developing …

[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II

TJ Schmidt, SA Khalid, AJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …

Patients' behavior regarding dietary or herbal supplements before and during COVID-19 in Saudi Arabia

LA Aldwihi, SI Khan, FF Alamri, Y AlRuthia… - International journal of …, 2021 - mdpi.com
The use of traditional medicinal plants in Saudi Arabia stems mainly from consumers' belief
in prophetic medicine. This study was conducted to explore changes in patients' use of …

A review of therapeutic potential of Saussurea lappa-An endangered plant from Himalaya

K Zahara, S Tabassum, S Sabir, M Arshad… - Asian Pacific journal of …, 2014 - Elsevier
There are 300 known Saussurea species. Among them, Saussurea lappa (S. lappa) is a
representative perennial herb, globally distributed across Himalaya region. S. lappa has …

Ethnopharmacologically important highly subsidized Indian medicinal plants: Systematic review on their traditional uses, phytochemistry, pharmacology, quality …

G Aggarwal, M Sharma, R Singh, U Sharma - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance India has an extensive reservoir of traditional wisdom and
a diverse range of medicinal plants that enrich its heritage. Plants have actively been used …

Sesquiterpene lactones: adverse health effects and toxicity mechanisms

MHR Amorim, RM Gil da Costa, C Lopes… - Critical reviews in …, 2013 - Taylor & Francis
Sesquiterpene lactones (STLs) present a wide range of biological activities, mostly based on
their alkylating capabilities, which underlie their therapeutic potential. These compounds are …

Aucklandia costus (syn. Saussurea costus): Ethnopharmacology of an endangered medicinal plant of the Himalayan region

RK Nadda, A Ali, RC Goyal, PK Khosla… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological relevance Aucklandia costus Falc. a medicinal plant is
native to the Himalayan region and synonymous with Saussurea costus, Saussurea lappa …

Concepts and technologies for tracking bioactive compounds in natural product extracts: generation of libraries, and hyphenation of analytical processes with …

O Potterat, M Hamburger - Natural product reports, 2013 - pubs.rsc.org
Covering: up to 2012Since the advent of high-throughput screening (HTS) in the early
1990s, a wealth of innovative technologies have been proposed and implemented for the …

Exploring the inhibitory potential of Saussurea costus and Saussurea involucrata phytoconstituents against the Spike glycoprotein receptor binding domain of SARS …

S Houchi, Z Messasma - Journal of Molecular Structure, 2022 - Elsevier
Abstract The B. 1.617. 2 Delta variant is considered to be the most infectious of all SARS-
CoV2 variants. Here, an attempt has been made through in-silico screening of 55 bioactive …

Sesquiterpene lactone! a promising antioxidant, anticancer and moderate antinociceptive agent from Artemisia macrocephala jacquem

M Shoaib, I Shah, N Ali, A Adhikari, MN Tahir… - … and alternative medicine, 2017 - Springer
Abstract Background Sesquiterpene lactones (STLs) make a diverse and huge group of bio-
active constituents that have been isolated from several plant families. However, the greatest …