Tumor‐targeting glycol chitosan nanoparticles for cancer heterogeneity
Nanomedicine is extensively employed for cancer treatment owing to its unique advantages
over conventional drugs and imaging agents. This increased attention to nanomedicine …
over conventional drugs and imaging agents. This increased attention to nanomedicine …
ABC transporters in breast cancer: their roles in multidrug resistance and beyond
ATP-binding cassette (ABC) transporters are membrane-spanning proteins involved in
cholesterol homeostasis, transport of various molecules in and out of cells and organelles …
cholesterol homeostasis, transport of various molecules in and out of cells and organelles …
[HTML][HTML] Pharmacogenetics of drug metabolism: the role of gene polymorphism in the regulation of doxorubicin safety and efficacy
AA Bagdasaryan, VN Chubarev, EA Smolyarchuk… - Cancers, 2022 - mdpi.com
Simple Summary The effectiveness and safety of the anti-cancer agent doxorubicin
(anthracycline group medicine) depend on the metabolism and retention of the drug in the …
(anthracycline group medicine) depend on the metabolism and retention of the drug in the …
Long non‐coding RNA FTH 1P3 activates paclitaxel resistance in breast cancer through miR‐206/ABCB 1
R Wang, T Zhang, Z Yang, C Jiang… - Journal of cellular and …, 2018 - Wiley Online Library
Emerging evidence has indicated the important function of long non‐coding RNA s (lnc RNA
s) in tumour chemotherapy resistance. However, the underlying mechanism is still …
s) in tumour chemotherapy resistance. However, the underlying mechanism is still …
[HTML][HTML] Pharmacogenetic Study of the Impact of ABCB1 Single Nucleotide Polymorphisms on the Response to Cyclosporine in Psoriasis Patients
A Chernov, D Kilina, T Smirnova, E Galimova - Pharmaceutics, 2022 - mdpi.com
Psoriasis is a chronic, T cell-mediated skin disease affecting 2–3% of the Caucasian
population. Cyclosporine A is a calcineurin inhibitor that acts selectively on T cells. The …
population. Cyclosporine A is a calcineurin inhibitor that acts selectively on T cells. The …
[HTML][HTML] Glycol chitosan-docosahexaenoic acid liposomes for drug delivery: synergistic effect of doxorubicin-rapamycin in drug-resistant breast cancer
Marine ecosystems are the most prevalent ecosystems on the planet, providing a diversity of
living organisms and resources. The development of nanotechnology may provide solutions …
living organisms and resources. The development of nanotechnology may provide solutions …
[HTML][HTML] Role of genetic variation in ABC transporters in breast cancer prognosis and therapy response
V Hlaváč, R Václavíková, V Brynychová… - International Journal of …, 2020 - mdpi.com
Breast cancer is the most common cancer in women in the world. The role of germline
genetic variability in ATP-binding cassette (ABC) transporters in cancer chemoresistance …
genetic variability in ATP-binding cassette (ABC) transporters in cancer chemoresistance …
Potential drug candidates as P-glycoprotein inhibitors to reverse multidrug resistance in cancer: an in silico drug discovery study
MAA Ibrahim, KAA Abdeljawaad… - Journal of …, 2023 - Taylor & Francis
The failure of chemotherapy in the treatment of carcinoma is mainly due to the development
of multidrug resistance (MDR), which is largely caused by the overexpression of P …
of multidrug resistance (MDR), which is largely caused by the overexpression of P …
Genetic influences in breast cancer drug resistance
A Daniyal, I Santoso, NHP Gunawan… - Breast cancer: targets …, 2021 - Taylor & Francis
Breast cancer is the most common cancer in adult women aged 20 to 50 years. The
therapeutic regimens that are commonly recommended to treat breast cancer are human …
therapeutic regimens that are commonly recommended to treat breast cancer are human …
Pharmacogenetics of antiemetics for chemotherapy-induced nausea and vomiting: a systematic review and meta-analysis
A Eliasen, K Dalhoff, R Mathiasen… - Critical Reviews in …, 2020 - Elsevier
A substantial proportion of cancer patients experience chemotherapy-induced nausea and
vomiting (CINV) despite the use of antiemetic drugs. Prevalent genetic polymorphisms …
vomiting (CINV) despite the use of antiemetic drugs. Prevalent genetic polymorphisms …