RGD engineered dendrimer nanotherapeutic as an emerging targeted approach in cancer therapy

A Sheikh, S Md, P Kesharwani - Journal of Controlled Release, 2021 - Elsevier
A bird's eye view is now demanded in the area of cancer research to suppress the suffering
of cancer patient and mediate the lack of treatment related to chemotherapy. Chemotherapy …

Naphthoquinones and derivatives as potential anticancer agents: An updated review

MM Rahman, MR Islam, S Akash, S Shohag… - Chemico-Biological …, 2022 - Elsevier
One of the leading global causes of death is cancer; even though several treatment methods
have improved survival rates, the incidence and fatality rates remain high. Naphthoquinones …

Cellular rewiring in lethal prostate cancer: the architect of drug resistance

M Carceles-Cordon, WK Kelly, L Gomella… - Nature reviews …, 2020 - nature.com
Over the past 5 years, the advent of combination therapeutic strategies has substantially
reshaped the clinical management of patients with advanced prostate cancer. However …

Non-coding RNAs in enzalutamide resistance of castration-resistant prostate cancer

K Gao, X Li, J Ni, B Wu, J Guo, R Zhang, G Wu - Cancer Letters, 2023 - Elsevier
Enzalutamide (Enz) is a next-generation androgen receptor (AR) antagonist used to treat
castration-resistant prostate cancer (CRPC). Unfortunately, the relapsing nature of CRPC …

[HTML][HTML] Growth inhibition and apoptosis in cancer cells induced by polyphenolic compounds of Acacia hydaspica: Involvement of multiple signal transduction …

T Afsar, JH Trembley, CE Salomon, S Razak… - Scientific reports, 2016 - nature.com
Acacia hydaspica R. Parker is known for its medicinal uses in multiple ailments. In this study,
we performed bioassay-guided fractionation of cytotoxic compounds from A. hydaspica and …

[HTML][HTML] Wnt/β-catenin signal transduction pathway in prostate cancer and associated drug resistance

C Wang, Q Chen, H Xu - Discover Oncology, 2021 - Springer
Globally, prostate cancer ranks second in cancer burden of the men. It occurs more
frequently in black men compared to white or Asian men. Usually, high rates exist for men …

[HTML][HTML] The Microwell-mesh: A high-throughput 3D prostate cancer spheroid and drug-testing platform

EO Mosaad, KF Chambers, K Futrega, JA Clements… - Scientific reports, 2018 - nature.com
Abstract Treatment following early diagnosis of Prostate cancer (PCa) is increasingly
successful, whilst the treatment of advanced and metastatic PCa remains challenging. A …

Role of exosomes in prostate cancer and male fertility

D Dey, S Ghosh, D Mirgh, SP Panda, NK Jha… - Drug Discovery …, 2023 - Elsevier
Prostate cancer (PCa) is the second most common and fifth most aggressive neoplasm
among men worldwide. In the last decade, extracellular vesicle (EV) research has decoded …

TGF‐β effects on prostate cancer cell migration and invasion require FosB

CSX Barrett, AC Millena, SA Khan - The Prostate, 2017 - Wiley Online Library
BACKGROUND Activator Protein‐1 (AP‐1) family (cJun, JunB, JunD, cFos, FosB, Fra1, and
Fra2) plays a central role in the transcriptional regulation of many genes that are associated …

The role of GATA2 in lethal prostate cancer aggressiveness

V Rodriguez-Bravo, M Carceles-Cordon… - Nature Reviews …, 2017 - nature.com
Advanced prostate cancer is a classic example of the intractability and consequent lethality
that characterizes metastatic carcinomas. Novel treatments have improved the survival of …