Air pollution and its effects on the immune system

DA Glencross, TR Ho, N Camina… - Free Radical Biology …, 2020 - Elsevier
A well-functioning immune system is vital for a healthy body. Inadequate and excessive
immune responses underlie diverse pathologies such as serious infections, metastatic …

Airway remodeling in asthma: what really matters

H Fehrenbach, C Wagner, M Wegmann - Cell and tissue research, 2017 - Springer
Airway remodeling is generally quite broadly defined as any change in composition,
distribution, thickness, mass or volume and/or number of structural components observed in …

[HTML][HTML] Air pollutants and early origins of respiratory diseases

D Kim, Z Chen, LF Zhou, SX Huang - Chronic diseases and translational …, 2018 - Elsevier
Air pollution is a global health threat and causes millions of human deaths annually. The late
onset of respiratory diseases in children and adults due to prenatal or perinatal exposure to …

Treatment trials in young patients with chronic obstructive pulmonary disease and pre–chronic obstructive pulmonary disease patients: time to move forward

FJ Martinez, A Agusti, BR Celli, MLK Han… - American journal of …, 2022 - atsjournals.org
Chronic obstructive pulmonary disease (COPD) is the end result of a series of dynamic and
cumulative gene–environment interactions over a lifetime. The evolving understanding of …

Outdoor air pollution and new-onset airway disease. An official American Thoracic Society workshop report

GD Thurston, JR Balmes, E Garcia… - Annals of the …, 2020 - atsjournals.org
Although it is well accepted that air pollution exposure exacerbates preexisting airway
disease, it has not been firmly established that long-term pollution exposure increases the …

Farm living: effects on childhood asthma and allergy

E Von Mutius, D Vercelli - Nature Reviews Immunology, 2010 - nature.com
Numerous epidemiological studies have shown that children who grow up on traditional
farms are protected from asthma, hay fever and allergic sensitization. Early-life contact with …

Remodeling in asthma

S Al-Muhsen, JR Johnson, Q Hamid - Journal of allergy and clinical …, 2011 - Elsevier
Airway remodeling encompasses the structural alterations in asthmatic compared with
normal airways. Airway remodeling in asthmatic patients involves a wide array of …

The association between environmental tobacco smoke exposure and childhood respiratory disease: a review

A Vanker, RP Gie, HJ Zar - Expert review of respiratory medicine, 2017 - Taylor & Francis
Introduction: Childhood respiratory illness is a major cause of morbidity and mortality
particularly in low and middle-income countries. Environmental tobacco smoke (ETS) …

Fibroblast-to-myofibroblast transition in bronchial asthma

M Michalik, K Wójcik-Pszczoła, M Paw, D Wnuk… - Cellular and Molecular …, 2018 - Springer
Bronchial asthma is a chronic inflammatory disease in which bronchial wall remodelling
plays a significant role. This phenomenon is related to enhanced proliferation of airway …

Risk factors for chronic obstructive pulmonary disease in a European cohort of young adults

R De Marco, S Accordini, A Marcon… - American journal of …, 2011 - atsjournals.org
Rationale: Few studies have investigated the factors associated with the early inception of
chronic obstructive pulmonary disease (COPD). Objectives: We investigated COPD risk …