Precision medicine and the future of cardiovascular diseases: a clinically oriented comprehensive review

Y Sethi, N Patel, N Kaka, O Kaiwan, J Kar… - Journal of clinical …, 2023 - mdpi.com
Cardiac diseases form the lion's share of the global disease burden, owing to the paradigm
shift to non-infectious diseases from infectious ones. The prevalence of CVDs has nearly …

The role of smoking in the mechanisms of development of chronic obstructive pulmonary disease and atherosclerosis

S Kotlyarov - International Journal of Molecular Sciences, 2023 - mdpi.com
Tobacco smoking is a major cause of chronic obstructive pulmonary disease (COPD) and
atherosclerotic cardiovascular disease (ASCVD). These diseases share common …

CD4+ T-lymphocytes exhibit biphasic kinetics post-myocardial infarction

V Kumar, SD Prabhu, SS Bansal - Frontiers in Cardiovascular …, 2022 - frontiersin.org
CD4+ T-cells facilitate wound healing post-myocardial infarction (MI) but promote left-
ventricular (LV) remodeling during ischemic heart failure (HF; 8 weeks post-MI). Therefore, it …

Shaping the future of cardiac wellness: exploring revolutionary approaches in disease management and prevention

TA Addissouky, IET El Sayed, MMA Ali… - Journal of Clinical …, 2024 - scientificarchives.com
Cardiovascular diseases (CVDs) remain a leading cause of morbidity and mortality
worldwide. Effective prevention and management strategies are essential to reduce the …

Impact of immunity on coronary artery disease: an updated pathogenic interplay and potential therapeutic strategies

N Laera, P Malerba, G Vacanti, S Nardin, M Pagnesi… - Life, 2023 - mdpi.com
Coronary artery disease (CAD) is the leading cause of death worldwide. It is a result of the
buildup of atherosclerosis within the coronary arteries. The role of the immune system in …

Efficacy of bioactive compounds in the regulation of metabolism and pathophysiology in cardiovascular diseases

VA Pawar, S Srivastava, A Tyagi, R Tayal… - Current Cardiology …, 2023 - Springer
Abstract Purpose of Review An imbalance in reactive oxygen species (ROS) homeostasis
can wreak damage to metabolic and physiological processes which can eventually lead to …

The heart as a target of vasopressin and other cardiovascular peptides in health and cardiovascular diseases

E Szczepanska-Sadowska - International Journal of Molecular Sciences, 2022 - mdpi.com
The automatism of cardiac pacemaker cells, which is tuned, is regulated by the autonomic
nervous system (ANS) and multiple endocrine and paracrine factors, including …

Myocardial inflammation in heart failure with reduced and preserved ejection fraction

P Alcaide, M Kallikourdis, R Emig… - Circulation Research, 2024 - Am Heart Assoc
Heart failure (HF) is characterized by a progressive decline in cardiac function and
represents one of the largest health burdens worldwide. Clinically, 2 major types of HF are …

Immune modulatory effects of ketogenic diet in different disease conditions

S Srivastava, VA Pawar, A Tyagi, KP Sharma, V Kumar… - Immuno, 2022 - mdpi.com
Interceding nutrients have been acquiring increased attention and prominence in the field of
healing and deterrence of various disorders. In this light, the present article encompasses …

The role of punicalagin and its metabolites in atherosclerosis and risk factors associated with the disease

S Alalawi, F Albalawi, DP Ramji - International journal of molecular …, 2023 - mdpi.com
Atherosclerotic cardiovascular disease (ACVD) is the leading cause of death worldwide.
Although current therapies, such as statins, have led to a marked reduction in morbidity and …