Bronchiectasis in children: diagnosis and treatment
Bronchiectasis is conventionally defined as irreversible dilatation of the bronchial tree.
Bronchiectasis unrelated to cystic fibrosis is an increasingly appreciated cause of chronic …
Bronchiectasis unrelated to cystic fibrosis is an increasingly appreciated cause of chronic …
Bronchiectasis
JD Chalmers, AB Chang, SH Chotirmall… - Nature reviews Disease …, 2018 - nature.com
Bronchiectasis refers to abnormal dilatation of the bronchi. Airway dilatation can lead to
failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms …
failure of mucus clearance and increased risk of infection. Pathophysiological mechanisms …
Pathophysiological mechanisms of asthma
A Bush - Frontiers in pediatrics, 2019 - frontiersin.org
The recent Lancet commission has highlighted that “asthma” should be used to describe a
clinical syndrome of wheeze, breathlessness, chest tightness, and sometimes cough. The …
clinical syndrome of wheeze, breathlessness, chest tightness, and sometimes cough. The …
ERS statement on protracted bacterial bronchitis in children
A Kantar, AB Chang, MD Shields… - European …, 2017 - Eur Respiratory Soc
This European Respiratory Society statement provides a comprehensive overview on
protracted bacterial bronchitis (PBB) in children. A task force of experts, consisting of …
protracted bacterial bronchitis (PBB) in children. A task force of experts, consisting of …
Management of children with chronic wet cough and protracted bacterial bronchitis: CHEST guideline and expert panel report
AB Chang, JJ Oppenheimer, MM Weinberger… - Chest, 2017 - Elsevier
Background Wet or productive cough is common in children with chronic cough. We
formulated recommendations based on systematic reviews related to the management of …
formulated recommendations based on systematic reviews related to the management of …
Protracted bacterial bronchitis in children: natural history and risk factors for bronchiectasis
DF Wurzel, JM Marchant, ST Yerkovich, JW Upham… - Chest, 2016 - Elsevier
Background Protracted bacterial bronchitis (PBB) and bronchiectasis are distinct diagnostic
entities that share common clinical and laboratory features. It is postulated, but remains …
entities that share common clinical and laboratory features. It is postulated, but remains …
Pediatric bronchiectasis: no longer an orphan disease
Bronchiectasis is described classically as a chronic pulmonary disorder characterized by a
persistent productive cough and irreversible dilatation of one or more bronchi. However, in …
persistent productive cough and irreversible dilatation of one or more bronchi. However, in …
Severe asthma in children
SK Ramratnam, LB Bacharier, TW Guilbert - The Journal of Allergy and …, 2017 - Elsevier
Severe asthma in children is associated with significant morbidity and is a highly
heterogeneous disorder with multiple clinical phenotypes. Cluster analyses have been …
heterogeneous disorder with multiple clinical phenotypes. Cluster analyses have been …
Advanced role of neutrophils in common respiratory diseases
J Liu, Z Pang, G Wang, X Guan, K Fang… - Journal of …, 2017 - Wiley Online Library
Respiratory diseases, always being a threat towards the health of people all over the world,
are most tightly associated with immune system. Neutrophils serve as an important …
are most tightly associated with immune system. Neutrophils serve as an important …
Outcomes of protracted bacterial bronchitis in children: a 5‐year prospective cohort study
TJC Ruffles, JM Marchant, IB Masters… - …, 2021 - Wiley Online Library
Background and objective Long‐term data on children with PBB has been identified as a
research priority. We describe the 5‐year outcomes for children with PBB to ascertain the …
research priority. We describe the 5‐year outcomes for children with PBB to ascertain the …